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Nature 448, 871-872 (23 August 2007) | doi:10.1038/448871a; Published online 22 August 2007
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Neuroscience: Obsessed with grooming
Steven E. Hyman1
Abstract
Roughly 2% of humans suffer from obsessive compulsive disorder, but a lack of animal models has impeded research into this condition. Could a genetically engineered mouse model provide an exciting lead?
Obsessive compulsive disorder (OCD) is one of a spectrum of disorders characterized by obsessions (intrusive, unwanted thoughts) and compulsions (ritualized behaviours intended to overcome the anxiety and tension resulting from the obsessions). Other similar conditions include Tourette's syndrome; sufferers with this disorder show several motor, and occasionally vocal, tics, often accompanied by obsessions and compulsions.
- Steven E. Hyman is in the Department of Neurobiology, Harvard Medical School, Massachusetts Hall, Cambridge, Massachusetts 02138, USA.
Email: seh@harvard.edu
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