Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 448, 871-872 (23 August 2007) | doi:10.1038/448871a; Published online 22 August 2007
Open Innovation Challenges
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
-
Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
- More Challenges
- Powered by:
nature jobs
Professorship
- Friedrich-Alexander-Universitat Erlangen-Nurnberg
- Erlangen 91054 Germany
Group Director Discovery Biology / Infectious Disease
- Bristol-Myers Squibb
- Wallingford, CT
Neuroscience: Obsessed with grooming
Steven E. Hyman1
Abstract
Roughly 2% of humans suffer from obsessive compulsive disorder, but a lack of animal models has impeded research into this condition. Could a genetically engineered mouse model provide an exciting lead?
Obsessive compulsive disorder (OCD) is one of a spectrum of disorders characterized by obsessions (intrusive, unwanted thoughts) and compulsions (ritualized behaviours intended to overcome the anxiety and tension resulting from the obsessions). Other similar conditions include Tourette's syndrome; sufferers with this disorder show several motor, and occasionally vocal, tics, often accompanied by obsessions and compulsions.
- Steven E. Hyman is in the Department of Neurobiology, Harvard Medical School, Massachusetts Hall, Cambridge, Massachusetts 02138, USA.
Email: seh@harvard.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Cerebral mitochondrial metabolism in early Parkinson's diseaseJournal of Cerebral Blood Flow & Metabolism Original Article
Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant miceNature Article (23 Aug 2007)
Multiple rare SAPAP3 missense variants in trichotillomania and OCDMolecular Psychiatry Letter
Fluvoxamine Treatment and D2 Receptors: a Pet Study on OCD Drug-Na???ve PatientsNeuropsychopharmacology Original Article
See all 6 matches for Research