Editor's Summary
23 August 2007
Inside story
The strength of network biology lies in its ability to derive cell biological information without a priori mechanistic or molecular knowledge. Eva Schmid and Harvey McMahon show that a molecular understanding of clathrin-mediated endocytosis, a process used by eukaryotic cells to pack nutrients and other molecules into vesicles for internalization, can refine the network approach and allow the derivation of general biological principles.
Analysis: Integrating molecular and network biology to decode endocytosis
Eva M. Schmid & Harvey T. McMahon
doi:10.1038/nature06031
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