Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 448, 762-763 (16 August 2007) | doi:10.1038/448762a; Published online 15 August 2007
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
- More Challenges
- Powered by:
nature jobs
Faculty Position in Mathematical Biology
- The Ohio State University
- Ohio, USA
Natural Products Chemist
- Praj Matrix - Praj Industries Ltd
- Pune, Maharashtra Pune-411021 India
Computational biochemistry: Models of transition
JoAnne Stubbe1
Abstract
Is it possible to determine the role of an enzyme from its structure? The latest findings suggest that it is, and prove the point by predicting the substrate for an enzyme of unknown function.
Although genomes are vast sources of information, not all of this information is currently understood. About 600 genomes have been completely characterized1, and have revealed thousands of DNA base sequences that could encode proteins — such sequences are known as open reading frames (ORFs).
- JoAnne Stubbe is in the Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.
Email: stubbe@mit.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Form finds functionNature Chemical Biology News and Views (01 Aug 2007)
New wine from old barrelsNature Structural Biology News and Views (01 Mar 2000)
See all 5 matches for News And ViewsRESEARCH
Structure-based activity prediction for an enzyme of unknown functionNature Article (16 Aug 2007)
Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamilyNature Chemical Biology Article (01 Dec 2008)
See all 4 matches for Research