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Nature 448, 757-758 (16 August 2007) | doi:10.1038/448757a; Published online 15 August 2007
Biochemistry: Designer enzymes
Michael P. Robertson1 & William G. Scott1
Abstract
Evolution has crafted thousands of enzymes that are efficient catalysts for a plethora of reactions. Human attempts at enzyme design trail far behind, but may benefit from exploiting evolutionary tactics.
Chemical reactions in living organisms are catalysed by enzymes, the vast majority of which are proteins. These finely tuned catalysts are the result of billions of years of evolution, and far surpass anything yet created by humans.
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