Table of contents
Volume 448 Number 7154 pp623-726
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Editorials
Strife on the seven seas p623
The sight of nations jockeying for position on the high seas is becoming more common. An international treaty exists to deal with such disputes and it is time for the US Senate to ratify it.
doi:10.1038/448623a
Clinical precision p623
Disease advocates should influence, but not dictate, research priorities.
doi:10.1038/448623b
A risky business p624
The White House risk-assessment bulletin should be put out of its misery.
doi:10.1038/448624a
News
Special reportAutism Speaks: the United States pays up p628
In recent years, autism has become the golden child of the fund-raising circuit. Meredith Wadman looks at a US public-relations success that is driving research funds and expertise towards this childhood condition, and asks who is missing out.
doi:10.1038/448628a
Chemists synthesize a natural-born killer p630
Neem-tree insecticide made in lab - but was it worth it?
Katharine Sanderson
doi:10.1038/448630a
A genetic switch for gender bending p630
Female mice adopt male sexual behaviour including pelvic thrusts and mounting.
Kerri Smith
doi:10.1038/448630b
US genetics bill blocked again p631
One-man lobby halts antidiscrimination law.
Meredith Wadman
doi:10.1038/448631a
Sidelines p632
doi:10.1038/448632a
Academic accused of living on borrowed lines p632
Allegations prompt fears over prevalence of plagiarism.
doi:10.1038/448632b
Strike threat over jailed primatologist p634
Treatment of rainforest researcher prompts protest by Brazilian scientists.
Erika Check & Thomas Hayden
doi:10.1038/448634a
Business
China tightens up p636
Plans to revamp drug regulation in China have yet to convince the sceptics, as Jane Qiu reports.
doi:10.1038/448636a
In brief p637
doi:10.1038/448637a
Market watch p637
Colin Macilwain
doi:10.1038/448637b
News Features
Cilia: Tails of the unexpected p638
No longer just cellular janitors, cilia are making a clean sweep for biological greatness. Claire Ainsworth explores how they may hold the secret of multicellular development.
doi:10.1038/448638a
See also: Editor's summary
Oceanography: Steaming ahead p642
India's new Ministry of Earth Sciences is at the helm of ambitious plans to advance deep-sea and polar research. K. S. Jayaraman reports.
doi:10.1038/448642a
See also: Editor's summary
Correspondence
Public engagement means listening as well as talking p644
Fern Wickson
doi:10.1038/448644a
Public engagement: both sides need to be realistic p644
Richard Wilson
doi:10.1038/448644b
Physics Nobels should favour inventions p644
Christoph Bartneck & Matthias Rauterberg
doi:10.1038/448644c
Traditional remedies put animal species at risk p644
Margaret B. Murphy
doi:10.1038/448644d
Commentary
New uses for old drugs p645
It takes too long and costs too much to bring new drugs to market. So let's beef up efforts to screen existing drugs for new uses, argue Curtis R. Chong and David J. Sullivan Jr.
doi:10.1038/448645a
Full Text | PDF (339K) | Supplementary information
See also: Editor's summary
Books and Arts
Social science goes virtual p647
Mathematical models could help us re-engage with reality rather than trying to reinvent it.
Philip Ball reviews Complex Adaptive Systems: An Introduction to Computational Models of Social Life by John H. Miller & Scott E. Page and Generative Social Science: Studies in Agent Based Computational Modeling by Joshua M. Epstein
doi:10.1038/448647a
In the eye of the storm p648
James Elsner reviews Storm World: Hurricanes, Politics, and the Battle Over Global Warming by Chris Mooney
doi:10.1038/448648a
Remarkable but not so unusual p649
Judith P. Zinsser reviews The Comet Sweeper: Caroline Herschel's Astronomical Ambition by Claire Brock
doi:10.1038/448649a
Exhibition: Famous faces p649
doi:10.1038/448649b
Exhibition: Palaeontology meets Hanna-Barbera p650
Colin Martin reviews The Homo species by Hyungkoo Lee
doi:10.1038/448650a
News and Views
Femtophysics: Double vision p651
By cunningly diffracting X-rays twice from an exploding nanometre-scale sphere, holographic images can be made of a tiny system evolving at lightning speed. The technique could be used to picture atomic dynamics.
Andrea Cavalleri
doi:10.1038/448651a
See also: Editor's summary
Systems neuroscience: Timing is everything p652
Interactions among neurons in brain circuits underlie sensory perception and information storage. Work in locusts shows how the timing of different neuronal signals is synchronized to ensure effective communication.
Phillip Larimer & Ben W. Strowbridge
doi:10.1038/448652a
See also: Editor's summary
50 & 100 Years Ago p653
doi:10.1038/448653a
Chemical biology: Ions illuminated p654
Calcium ions act as signals between cells, but their exact locations — at the nanometre scale — have been difficult to pinpoint. The latest biosensor promises to reveal these details in dynamic living systems.
Christopher J. Chang
doi:10.1038/448654a
Geochemistry: The lost continents p655
Once subducted into the mantle, material from Earth's continental crust seems to disappear. But its distinctive isotopic signature has been found back at the surface — in volcanic rocks on a Pacific island.
Albrecht W. Hofmann
doi:10.1038/448655a
See also: Editor's summary
Electrostatics: Colour discrimination p656
Richard Webb
doi:10.1038/448656a
Biodiversity: World of insects p657
When it comes to understanding patterns of biodiversity, ours is a little-known planet. Large-scale sampling projects, as carried out in two investigations of insect diversity, show a way forward.
Nigel E. Stork
doi:10.1038/448657a
See also: Editor's summary
Crystallography: A down-to-Earth approach p658
In seeking out ideal conditions for growing protein crystals, solutions have increasingly been found in the low-gravity conditions of space. But answers might be lurking in fields closer to home.
John R. Helliwell & Naomi E. Chayen
doi:10.1038/448658a
Plant biology: Jasmonate perception machines p659
How do plant cells respond so vigorously to organisms that damage their cells? Following on from progress made in understanding hormonal control of growth and development comes news of how a plant's security system operates.
Edward E. Farmer
doi:10.1038/448659a
See also: Editor's summary
Correction p660
doi:10.1038/448660a
Brief Communications Arising
Crystallography: Crystallographic evidence for deviating C3b structure pE1
Bert J. C. Janssen, Randy J. Read, Axel T. Brünger & Piet Gros
doi:10.1038/nature06102
First paragraph | Full Text | PDF (2,605K)
Crystallography: Crystallographic evidence for deviating C3b structure (Reply) pE2
A. Abdul Ajees, Krishnasamy Gunasekaran, Sthanam V. L. Narayana & H. M. Krishna Murthy
doi:10.1038/nature06103
First paragraph | Full Text | PDF (2,605K)
Articles
JAZ repressor proteins are targets of the SCFCOI1 complex during jasmonate signalling p661
Bryan Thines, Leron Katsir, Maeli Melotto, Yajie Niu, Ajin Mandaokar, Guanghui Liu, Kinya Nomura, Sheng Yang He, Gregg A. Howe & John Browse
doi:10.1038/nature05960
Abstract | Full Text | PDF (914K) | Supplementary information
See also: Editor's summary | News and Views by Farmer
The JAZ family of repressors is the missing link in jasmonate signalling p666
A. Chini, S. Fonseca, G. Fernández, B. Adie, J. M. Chico, O. Lorenzo, G. García-Casado, I. López-Vidriero, F. M. Lozano, M. R. Ponce, J. L. Micol & R. Solano
doi:10.1038/nature06006
Abstract | Full Text | PDF (2,437K) | Supplementary information
See also: Editor's summary | News and Views by Farmer
Letters
Strong dipolar effects in a quantum ferrofluid p672
Thierry Lahaye, Tobias Koch, Bernd Fröhlich, Marco Fattori, Jonas Metz, Axel Griesmaier, Stefano Giovanazzi & Tilman Pfau
doi:10.1038/nature06036
First paragraph | Full Text | PDF (372K)
See also: Editor's summary
Femtosecond time-delay X-ray holography p676
Henry N. Chapman,
Stefan P. Hau-Riege,
Michael J. Bogan,
Sa
a Bajt,
Anton Barty,
Sébastien Boutet,
Stefano Marchesini,
Matthias Frank,
Bruce W. Woods,
W. Henry Benner,
Richard A. London,
Urs Rohner,
Abraham Szöke,
Eberhard Spiller,
Thomas Möller,
Christoph Bostedt,
David A. Shapiro,
Marion Kuhlmann,
Rolf Treusch,
Elke Plönjes,
Florian Burmeister,
Magnus Bergh,
Carl Caleman,
Gösta Huldt,
M. Marvin Seibert
&
Janos Hajdu
doi:10.1038/nature06049
First paragraph | Full Text | PDF (964K)
See also: Editor's summary | News and Views by Cavalleri
Intense mixing of lower thermocline water on the crest of the Mid-Atlantic Ridge p680
Louis C. St Laurent & Andreas M. Thurnherr
doi:10.1038/nature06043
First paragraph | Full Text | PDF (840K)
See also: Editor's summary
The return of subducted continental crust in Samoan lavas p684
Matthew G. Jackson, Stanley R. Hart, Anthony A. P. Koppers, Hubert Staudigel, Jasper Konter, Jerzy Blusztajn, Mark Kurz & Jamie A. Russell
doi:10.1038/nature06048
First paragraph | Full Text | PDF (426K) | Supplementary information
See also: Editor's summary | News and Views by Hofmann
Implications of new early Homo fossils from Ileret, east of Lake Turkana, Kenya p688
F. Spoor, M. G. Leakey, P. N. Gathogo, F. H. Brown, S. C. Antón, I. McDougall, C. Kiarie, F. K. Manthi & L. N. Leakey
doi:10.1038/nature05986
First paragraph | Full Text | PDF (659K) | Supplementary information
See also: Editor's summary
Low beta diversity of herbivorous insects in tropical forests p692
Vojtech Novotny, Scott E. Miller, Jiri Hulcr, Richard A. I. Drew, Yves Basset, Milan Janda, Gregory P. Setliff, Karolyn Darrow, Alan J. A. Stewart, John Auga, Brus Isua, Kenneth Molem, Markus Manumbor, Elvis Tamtiai, Martin Mogia & George D. Weiblen
doi:10.1038/nature06021
First paragraph | Full Text | PDF (446K) | Supplementary information
See also: Editor's summary | News and Views by Stork
Host specificity of Lepidoptera in tropical and temperate forests p696
L. A. Dyer, M. S. Singer, J. T. Lill, J. O. Stireman, G. L. Gentry, R. J. Marquis, R. E. Ricklefs, H. F. Greeney, D. L. Wagner, H. C. Morais, I. R. Diniz, T. A. Kursar & P. D. Coley
doi:10.1038/nature05884
First paragraph | Full Text | PDF (311K) | Supplementary information
See also: Editor's summary | News and Views by Stork
A gastrin-releasing peptide receptor mediates the itch sensation in the spinal cord p700
Yan-Gang Sun & Zhou-Feng Chen
doi:10.1038/nature06029
First paragraph | Full Text | PDF (2,193K) | Supplementary information
See also: Editor's summary
Global changes to the ubiquitin system in Huntington's disease p704
Eric J. Bennett, Thomas A. Shaler, Ben Woodman, Kwon-Yul Ryu, Tatiana S. Zaitseva, Christopher H. Becker, Gillian P. Bates, Howard Schulman & Ron R. Kopito
doi:10.1038/nature06022
First paragraph | Full Text | PDF (453K) | Supplementary information
See also: Editor's summary
Hebbian STDP in mushroom bodies facilitates the synchronous flow of olfactory information in locusts p709
Stijn Cassenaer & Gilles Laurent
doi:10.1038/nature05973
First paragraph | Full Text | PDF (727K) | Supplementary information
See also: Editor's summary | News and Views by Larimer & Strowbridge
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA p714
Steen K. T. Ooi, Chen Qiu, Emily Bernstein, Keqin Li, Da Jia, Zhe Yang, Hediye Erdjument-Bromage, Paul Tempst, Shau-Ping Lin, C. David Allis, Xiaodong Cheng & Timothy H. Bestor
doi:10.1038/nature05987
First paragraph | Full Text | PDF (457K) | Supplementary information
Recognition of unmethylated histone H3 lysine 4 links BHC80 to LSD1-mediated gene repression p718
Fei Lan, Robert E. Collins, Rossella De Cegli, Roman Alpatov, John R. Horton, Xiaobing Shi, Or Gozani, Xiaodong Cheng & Yang Shi
doi:10.1038/nature06034
First paragraph | Full Text | PDF (985K) | Supplementary information
Naturejobs
ProspectProspects p723
Lab loves lost and found: readers respond.
Gene Russo
doi:10.1038/nj7154-723a
Futures
What I did on my holidays p726
Travel broadens the mind.
Ian Stewart
doi:10.1038/448726a