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Nature 448, 600-603 (2 August 2007) | doi:10.1038/nature06041;
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Behavioural improvements with thalamic stimulation after severe traumatic brain injury
Widespread loss of cerebral connectivity is assumed to underlie the failure of brain mechanisms that support communication and goal-directed behaviour following severe traumatic brain injury. Disorders of consciousness that persist for longer than 12 months after severe traumatic brain injury are generally considered to be immutable; no treatment has been shown to accelerate recovery or improve functional outcome in such cases.
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