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Nature 448, 591-594 (15 July 2007) | doi:10.1038/nature06010;
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A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
Type 1 diabetes (T1D) in children results from autoimmune destruction of pancreatic beta cells, leading to insufficient production of insulin. A number of genetic determinants of T1D have already been established through candidate gene studies, primarily within the major histocompatibility complex but also within other loci.
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