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Nature 448, 548-549 (2 August 2007) | doi:10.1038/448548a; Published online 1 August 2007
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Genomic biology: The epigenomic era opens
Stephen B. Baylin1 & Kornel E. Schuebel1
Abstract
Readout of information from the genome depends on intricate regulation of how DNA is packaged by proteins. The great endeavour to reveal how this packaging operates pan-genomically is now under way.
A new era is opening for biologists involved in understanding cellular systems. It is exemplified by papers by Mikkelsen et al.page 553 of this issue)1 and Barski et al.Cell)2 — they describe the kind of unprecedented insights that are emerging from investigations of how a single mammalian genome can be regulated to produce different cell types.
- Stephen B. Baylin and Kornel E. Schuebel are at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, 401 North Broadway, Baltimore, Maryland 21231, USA.
Email: sbaylin@jhmi.edu
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