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Nature 448, 545-546 (2 August 2007) | doi:10.1038/448545a; Published online 1 August 2007
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Cancer: Broken genes in solid tumours
Matthew Meyerson1
Abstract
Mutations that cause portions of two genes to fuse together and form a hybrid gene are frequent in blood-related cancers. New findings implicate one such fusion gene in the most common type of lung cancer.
Lung cancer is the main cause of cancer deaths throughout the world1, with an annual fatality of more than 1 million. Non-small-cell lung cancer (NSCLC) accounts for about 80% of all lung cancer cases.
- Matthew Meyerson is at the Dana-Farber Cancer Institute, 44 Binney Street, Boston, Massachusetts 02115, USA.
Email: matthew_meyerson@dfci.harvard.edu
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