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Nature 448, 530-532 (2 August 2007) | doi:10.1038/448530a; Published online 1 August 2007

Open Innovation Challenges

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Human-subjects research: Trial and error

Heidi Ledford1

  1. Heidi Ledford writes for Nature from Boston, Massachusetts.

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The ethics committees that oversee research done in humans have been attacked from all sides. Heidi Ledford recounts the struggle to come up with alternatives.

Fourteen years of treating people with tuberculosis has taught physician William Burman what to expect when a patient walks through his door. Tuberculosis is not typically a disease of the well-heeled.