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Nature 448, 474-479 (13 June 2007) | doi:10.1038/nature05935;
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Protective and therapeutic role for |[agr]|B-crystallin in autoimmune demyelination
|[agr]|B-crystallin (CRYAB) is the most abundant gene transcript present in early active multiple sclerosis lesions, whereas such transcripts are absent in normal brain tissue. This crystallin has anti-apoptotic and neuroprotective functions.
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