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Nature 448, 415-416 (26 July 2007) | doi:10.1038/448415a; Published online 25 July 2007
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Postdoctoral Fellow in Immunology
- The Scripps Research Institute
- N Torrey Pines Rd, San Diego, CA, USA
Assistant Manager-Pharma / CRO-Global Strategic Sourcing
- Varda Biotech
- Mumbai India
Biochemistry: Uncharted route for antibiotics
John P. Quinn1
Abstract
In their battle for survival, soil microorganisms produce a vast arsenal of toxic molecules. One such toxin contains a unique sequence of atoms, and its biosynthesis includes some unexpected steps.
Many commercially available antibiotics are products of soil bacteria that belong to the genus Streptomyces, or are modified versions of those products. They include several that are vital to medicine, such as vancomycin, rifampicin and clavulanic acid.
- John P. Quinn is at the School of Biological Sciences, Queen's University, 97 Lisburn Road, Belfast BT9 7BL, Northern Ireland.
Email: j.quinn@qub.ac.uk
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