Figures and Tables
From the following article:
Non-transcriptional control of DNA replication by c-Myc
David Dominguez-Sola, Carol Y. Ying, Carla Grandori, Luca Ruggiero, Brenden Chen, Muyang Li, Denise A. Galloway, Wei Gu, Jean Gautier & Riccardo Dalla-Favera
Nature 448, 445-451(26 July 2007)
doi:10.1038/nature05953
Figure 1
Myc interacts with the pre-replicative complex in mammalian cells.
Full size figure and legend (299K)Figure 2
Myc co-localizes with early DNA synthesis foci and binds the Myc gene replication origin.
Full size figure and legend (178K)Figure 3
Myc is required for efficient DNA replication and proper origin specification in the absence of transcription.
Full size figure and legend (192K)Figure 4
Relationship between Myc protein levels and the number of active DNA replication origins.
Full size figure and legend (228K)Figure 5
Myc deregulation induces replication-dependent DNA damage.
Full size figure and legend (267K)




