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News and Views
Nature 448, 260-262 (19 July 2007) | doi:10.1038/448260a; Published online 18 July 2007
Stem cells: The magic brew
Janet Rossant1
Abstract
Researchers have engineered embryonic stem-like cells from normal mouse skin cells. If this method can be translated to humans, patient-specific stem cells could be made without the use of donated eggs or embryos.
Two reports in this issue1, 2 and one elsewhere3 describe a seemingly simple method for changing differentiated adult cells into pluripotent stem cells. The 'gold-standard' test for pluripotency is the ability of a cell to contribute extensively to all adult cell types, including the germ line.
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