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News and Views
Nature 448, 260-262 (19 July 2007) | doi:10.1038/448260a; Published online 18 July 2007
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Stem cells: The magic brew
Janet Rossant1
Abstract
Researchers have engineered embryonic stem-like cells from normal mouse skin cells. If this method can be translated to humans, patient-specific stem cells could be made without the use of donated eggs or embryos.
Two reports in this issue1, 2 and one elsewhere3 describe a seemingly simple method for changing differentiated adult cells into pluripotent stem cells. The 'gold-standard' test for pluripotency is the ability of a cell to contribute extensively to all adult cell types, including the germ line.
- Janet Rossant is in the Program in Developmental and Stem Cell Biology, Hospital for Sick Children Research Institute, and the Department of Medical Genetics and Microbiology, University of Toronto, 555 University Avenue, Toronto, Ontario M5G 1X8, Canada.
Email: janet.rossant@sickkids.ca
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