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Nature 448, 196-199 (27 June 2007) | doi:10.1038/nature05972;
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New cell lines from mouse epiblast share defining features with human embryonic stem cells
The application of human embryonic stem (ES) cells in medicine and biology has an inherent reliance on understanding the starting cell population. Human ES cells differ from mouse ES cells and the specific embryonic origin of both cell types is unclear.
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