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Editorials

A geographical error p105

The most suitably qualified person should secure an important post, in almost all instances. But competing interests among nations mean that this is not always the case in Europe.

doi:10.1038/448105a


Safety clause p105

US research on bioweapons has expanded rapidly, without sufficiently transparent regulation.

doi:10.1038/448105b


Hard to swallow p105

Is it possible to gauge the true potential of traditional Chinese medicine?

doi:10.1038/448106a

See also: Editor's summary


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Research Highlights

Research highlights p108

doi:10.1038/448108a


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News

HIV trial doomed by design, say critics p110

Microbicide gel dosage prompts call for rethink.

Erika Check

doi:10.1038/448110a


Conserving life and livelihood p111

Does conservation really benefit the poor?

Emma Marris

doi:10.1038/448111a


Sidelines p112

doi:10.1038/448112a


Austria's science institute gathers steam p112

Plan for graduate-level facility back on track.

Carina Lenotti

doi:10.1038/448112b


Snapshot: Marks of distinction p113

Historians follow paper trail for artistic etching.

Alison Abbott

doi:10.1038/448113a


French universities to gain control p113

President Sarkozy promises freedom in his reform bill.

Declan Butler

doi:10.1038/448113b


Fly library boosts gene tool supply p115

Massive collection of transgenic Drosophila spreads its wings.

Heidi Ledford

doi:10.1038/448115a

See also: Editor's summary


Activated eggs offer route to stem cells p116

Technique could sidestep need for viable embryos.

David Cyranoski

doi:10.1038/448116a


News in brief p117

doi:10.1038/448117a


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Column

Party of One

Technical advice p119

Scientists tend to complain that Congress rarely pays heed to what they have to say. But the issues are often as much about values as they are science, says David Goldston.

David Goldston

doi:10.1038/448119a


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Business

Civil aviation faces green challenge p120

As a fast-growing emitter of greenhouse gases, the aviation industry is under intense pressure to improve its fuel efficiency. Kurt Kleiner surveys its options.

doi:10.1038/448120a


In brief p121

doi:10.1038/448121a


Market watch p121

doi:10.1038/448121b


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News Features

Mass extinctions: Reading the book of death p122

Studies of mass extinctions tend to emphasize the sheer scope of the carnage. But subtle differences between the species that died and those that survived can be crucial, finds Nick Lane.

doi:10.1038/448122a

See also: Editor's summary


Traditional medicine: A culture in the balance p126

Traditional Chinese medicine and Western science face almost irreconcilable differences. Can systems biology bring them together? Jane Qiu reports.

doi:10.1038/448126a

See also: Editor's summary


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Correspondence

Authors' financial interests should be made known to manuscript reviewers p129

Inmaculada de Melo-Martín & Kristen Intemann

doi:10.1038/448129a


Space-time safe — at least until the LHC switches on p129

Thomas Dent

doi:10.1038/448129b


Mentors could support a student reviewer database p129

Angelo P. Pernetta

doi:10.1038/448129c


Mentors: public lists would help students choose p129

Ben Barres

doi:10.1038/448129d


How incompatibilities may have led to eukaryotic cell p130

Yaacov Davidov & Edouard Jurkevitch

doi:10.1038/448130a


Text mining: powering the database revolution p130

Udo Hahn, Joachim Wermter, Rainer Blasczyk & Peter A. Horn

doi:10.1038/448130b


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Commentary

Beyond the troubled relationship p131

If scientific culture in the Muslim world has changed since the golden era of Islamic science, so has the practice of Islam. Reintroducing knowledge and creativity requires a revival of both, argues Ziauddin Sardar.

doi:10.1038/448131a

See also: Editor's summary


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Books and Arts

Imagine a better world p135

Given that humans are here to stay on Earth for some time yet, what can we do to lessen our impact?

Stuart L. Pimm reviews The World Without Us by Alan Weisman

doi:10.1038/448135a


Degrees of change p136

Stefan Rahmstorf reviews Six Degrees: Our Future on a Hotter Planet by Mark Lynas

doi:10.1038/448136a


Culture costs lives p137

Michael B. A. Oldstone reviews Vaccine: The Controversial Story of Medicine's Greatest Lifesaver by Arthur Allen

doi:10.1038/448137a


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Essay

Linnaeus and taxonomy in Japan p139

Doctors at the Dutch Trading House on Dejima were a conduit for science into and out of Europe.

His Majesty The Emperor of Japan

doi:10.1038/448139a

See also: Editor's summary


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News and Views

Photonics: Light in chains p141

Diffraction places a fundamental limit on the smallest scales at which light can be controlled. A nanoscale silver array not only circumvents the barrier, but steers different-coloured light to different places.

Niek F. van Hulst

doi:10.1038/448141a


Gene transcription: Extending the message p142

During transcription, RNA polymerase catalyses the addition of nucleotides to the growing RNA chain. High-resolution structural snapshots indicate that the polymerase first identifies its substrate, and then incorporates it.

Patrick Cramer

doi:10.1038/448142a

See also: Editor's summary


Extrasolar planets: Water on distant worlds p143

Is the presence of water a feature common to all gas-giant planets? The first convincing detection of water vapour in the atmosphere of such a planet from outside our Solar System indicates that the answer is yes.

Heather A. Knutson

doi:10.1038/448143a

See also: Editor's summary


Plant ecology: Family roots p145

Experiments in which related and unrelated plants were grown together reveal the ability of roots to recognize their kin. The ecological and evolutionary implications are tantalizing topics for future studies.

Ragan M. Callaway & Bruce E. Mahall

doi:10.1038/448145a


50 & 100 Years Ago p146

doi:10.1038/448146a


Neurophysiology: Channelling cold reception p147

Perception of cold and hot is one of life's essentials. Three research teams find that, when a temperature-sensing receptor is deleted in mice, the animals lose their response to a range of cold temperatures.

Bernd Nilius & Thomas Voets

doi:10.1038/448147a

See also: Editor's summary


Toxicology: Danger in the diet p148

Tim Lincoln

doi:10.1038/448148a


Obituary: Pierre-Gilles de Gennes (1932–2007) p149

Pioneer of soft-matter physics.

Françoise Brochard-Wyart

doi:10.1038/448149a


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Articles

A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila p151

Georg Dietzl, Doris Chen, Frank Schnorrer, Kuan-Chung Su, Yulia Barinova, Michaela Fellner, Beate Gasser, Kaolin Kinsey, Silvia Oppel, Susanne Scheiblauer, Africa Couto, Vincent Marra, Krystyna Keleman & Barry J. Dickson

doi:10.1038/nature05954

See also: Editor's summary


Structural basis for transcription elongation by bacterial RNA polymerase p157

Dmitry G. Vassylyev, Marina N. Vassylyeva, Anna Perederina, Tahir H. Tahirov & Irina Artsimovitch

doi:10.1038/nature05932

See also: Editor's summary | News and Views by Cramer


Structural basis for substrate loading in bacterial RNA polymerase p163

Dmitry G. Vassylyev, Marina N. Vassylyeva, Jinwei Zhang, Murali Palangat, Irina Artsimovitch & Robert Landick

doi:10.1038/nature05931

See also: Editor's summary | News and Views by Cramer


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Letters

Water vapour in the atmosphere of a transiting extrasolar planet p169

Giovanna Tinetti, Alfred Vidal-Madjar, Mao-Chang Liang, Jean-Philippe Beaulieu, Yuk Yung, Sean Carey, Robert J. Barber, Jonathan Tennyson, Ignasi Ribas, Nicole Allard, Gilda E. Ballester, David K. Sing & Franck Selsis

doi:10.1038/nature06002

See also: Editor's summary | News and Views by Knutson


Compositional homogeneity in the fragmented comet 73P/Schwassmann–Wachmann 3 p172

N. Dello Russo, R. J. Vervack, H. A. Weaver, N. Biver, D. Bockelée-Morvan, J. Crovisier & C. M. Lisse

doi:10.1038/nature05908

See also: Editor's summary


High-resolution spectroscopy of two-dimensional electron systems p176

O. E. Dial, R. C. Ashoori, L. N. Pfeiffer & K. W. West

doi:10.1038/nature05982


Reversal of the net dinitrogen gas flux in coastal marine sediments p180

R. W. Fulweiler, S. W. Nixon, B. A. Buckley & S. L. Granger

doi:10.1038/nature05963

See also: Editor's summary


Spreading rate dependence of gravity anomalies along oceanic transform faults p183

Patricia M. Gregg, Jian Lin, Mark D. Behn & Laurent G. J. Montési

doi:10.1038/nature05962


Biodiversity and ecosystem multifunctionality p188

Andy Hector & Robert Bagchi

doi:10.1038/nature05947

See also: Editor's summary


Derivation of pluripotent epiblast stem cells from mammalian embryos p191

I. Gabrielle M. Brons, Lucy E. Smithers, Matthew W. B. Trotter, Peter Rugg-Gunn, Bowen Sun, Susana M. Chuva de Sousa Lopes, Sarah K. Howlett, Amanda Clarkson, Lars Ahrlund-Richter, Roger A. Pedersen & Ludovic Vallier

doi:10.1038/nature05950

See also: Editor's summary


New cell lines from mouse epiblast share defining features with human embryonic stem cells p196

Paul J. Tesar, Josh G. Chenoweth, Frances A. Brook, Timothy J. Davies, Edward P. Evans, David L. Mack, Richard L. Gardner & Ronald D. G. McKay

doi:10.1038/nature05972

See also: Editor's summary


An intracellular P2X receptor required for osmoregulation in Dictyostelium discoideum p200

Samuel J. Fountain, Katie Parkinson, Mark T. Young, Lishuang Cao, Christopher R. L. Thompson & R. Alan North

doi:10.1038/nature05926


The menthol receptor TRPM8 is the principal detector of environmental cold p204

Diana M. Bautista, Jan Siemens, Joshua M. Glazer, Pamela R. Tsuruda, Allan I. Basbaum, Cheryl L. Stucky, Sven-Eric Jordt & David Julius

doi:10.1038/nature05910

See also: Editor's summary | News and Views by Nilius & Voets


An efflux transporter of silicon in rice p209

Jian Feng Ma, Naoki Yamaji, Namiki Mitani, Kazunori Tamai, Saeko Konishi, Toru Fujiwara, Maki Katsuhara & Masahiro Yano

doi:10.1038/nature05964

See also: Editor's summary


Antitumour drugs impede DNA uncoiling by topoisomerase I p213

Daniel A. Koster, Komaraiah Palle, Elisa S. M. Bot, Mary-Ann Bjornsti & Nynke H. Dekker

doi:10.1038/nature05938

See also: Editor's summary


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Naturejobs

Prospect

Government-funded labs have their perks, and their challenges p219

Gene Russo

doi:10.1038/nj7150-219a


Special Report

Fighting Back p220

Emerging from scandal and reorganization, Los Alamos National Laboratory hopes to retain talent and remain at the cutting edge. Karen Fox reports.

Karen Fox

doi:10.1038/nj7150-220a


Career Views

France Córdova, president, Purdue University, West Lafayette, Indiana p222

France Córdova becomes Purdue University's president.

Virginia Gewin

doi:10.1038/nj7150-222a


Engineering a place for women p222

Everyday workplace culture might be keeping women out of science, engineering and technology fields in Britain.

Roger Livesey

doi:10.1038/nj7150-222b


(Almost) in press p222

Composing a manuscript is a laborious task. Could there be a better way some day?

Peter Jordan

doi:10.1038/nj7150-222c


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Futures

A piratical sabbatical p224

It's just too good to be true.

Ian Whates

doi:10.1038/448224a


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