Experimental foragers put 100-year-old mimicry debate to the test.
doi:10.1038/7149xiiia
Table of contents
Volume 448 Number 7149 pp1-104
(this content only available online) indicates content that is available online only
Making the paper: Hannah Rowland pxiii
Abstractions pxiii
doi:10.1038/7149xiiib
From the blogosphere pxiii
doi:10.1038/7149xiiic
Top of page
Editorials
Parallel worlds galore p1
The 50th anniversary of an astonishing scientific hypothesis deserves celebration. So too do the truly astounding tales of a literary genre that anticipated it.
doi:10.1038/448001a
Enough talk already p1
Governments should act on researchers' attempts to engage the public over nanotechnology.
doi:10.1038/448001b
Discriminating on genes p2
The United States is belatedly establishing necessary protections in law. Others, take note.
doi:10.1038/448002a
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News
The petaflop challenge p6
Future supercomputers could leave scientists scrabbling for software.
Declan Butler
doi:10.1038/448006a
UK science reshuffled p7
No solar hiding place for greenhouse sceptics p8
Cosmic-ray results auger well for future p8
The great gig in the South p9
Live Earth unleashes its Antarctic monkeys.
Katharine Sanderson
doi:10.1038/448009a
Sidelines p10
doi:10.1038/448010a
Faster still and faster p10
War of words erupts over fossil dig p12
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Business
Abbott's AIDS fight-back p14
Most drug companies have tried to avoid making enemies of AIDS activist groups. But Abbott Laboratories' patience has snapped, as Erika Check reports.
doi:10.1038/448014a
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News Features
Many worlds: See me here, see me there p15
Fifty years ago, a physics student dissatisfied with the standard view of quantum mechanics came up with a radical new interpretation. Mark Buchanan reports on the ensuing debate.
Mark Buchanan
doi:10.1038/448015a
The biologists strike back p18
Time machines, spaceships, atomic blasters — the icons of science fiction tend to come from the physical sciences. But science fiction has a biological side too, finding drama and pathos in everything from alien evolution to the paradoxes of consciousness. Nature brought together four science-fiction writers with a background in the biological sciences to talk about life-science fiction.
doi:10.1038/448018a
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Correspondence
Not so good when 75% of grant applications fail p22
Admission that intelligent design is a religious view p22
Terrorists are activists who renounce non-violence p22
Activists: arson risks killing innocent people p22
Activists: some walls are not meant to be breached p22
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Commentary
Many lives in many worlds p23
Accepting quantum physics to be universally true, argues Max Tegmark, means that you should also believe in parallel universes.
Max Tegmark
doi:10.1038/448023a
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Books and Arts
Surfing the multiverse p25
The 'many worlds' of quantum mechanics spawned many more of science fiction.
Gary Wolfe
doi:10.1038/448025a
Exhibition: Art shadowing science p26
doi:10.1038/448026a
Falling victim to balance p27
Science with flare p27
A greener education p28
doi:10.1038/448028a
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Essay
ConceptAstronomy: A constant surprise p29
Whether ancient or new, in distant galaxies or our own cosmic back-yard, stars have dramatic similarities that hint at remarkably robust formative processes.
John Cowan
doi:10.1038/448029a
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News and Views
火星：粘土に刻まれた太古の痕跡
Mars: Ancient fingerprints in the clay p31
The thermodynamics of ancient clays on Mars seems inconsistent with the idea that a thick atmosphere of carbon dioxide caused a warm, wet era in the planet's early history. What did cause it remains an enigma.
David C. Catling
doi:10.1038/448031a
日本語要約 | Full Text | PDF (368K)
合成生物学：生命をデザインする
Synthetic biology: Designs for life p32
The genome of one bacterium has been successfully replaced with that of a different bacterium, transforming one species into another. This development is a harbinger of whole-genome engineering for practical ends.
Philip Ball
doi:10.1038/448032a
日本語要約 | Full Text | PDF (336K)
分子医学：入室許可
Molecular medicine: Entry granted p33
The inability to efficiently deliver small interfering RNAs to target organs hinders their therapeutic application. So a demonstration of siRNA delivery to a notoriously difficult organ — the brain — is very exciting indeed.
Edouard M. Cantin & John J. Rossi
doi:10.1038/448033a
日本語要約 | Full Text | PDF (364K)
進化生物学：すれすれの擬態
Evolutionary biology: Mimicry on the edge p34
The latest turn in studies of mimicry in the animal world involves great tits as predators and almonds as prey. When it comes to being unpalatable, it seems that some mimics may neither flatter nor deceive.
Thomas N. Sherratt
doi:10.1038/448034a
日本語要約 | Full Text | PDF (468K)
50 & 100 Years Ago p35
免疫学：T細胞が糖を区別する方法
Immunology: How a T cell sees sugar p36
T cells of the immune system recognize lipids, as well as peptides, extending our ideas about such target antigens. A crystal structure of a T-cell receptor docked to antigen shows how a sugar controls lipid recognition.
D. Branch Moody
doi:10.1038/nature05890
日本語要約 | Full Text | PDF (415K)
惑星科学：スポンジのヒペリオン
Planetary science: Hyperion the sponge p37
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Articles
医学：中枢神経系への低分子干渉RNAの経血管的送達
Transvascular delivery of small interfering RNA to the central nervous system p39
Priti Kumar, Haoquan Wu, Jodi L. McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L. Davidson, Sang Kyung Lee, Premlata Shankar & N. Manjunath
doi:10.1038/nature05901
免疫：半不変なNKT T細胞受容体によるCD1d-脂質抗原の認識
CD1d–lipid-antigen recognition by the semi-invariant NKT T-cell receptor p44
Natalie A. Borg, Kwok S. Wun, Lars Kjer-Nielsen, Matthew C. J. Wilce, Daniel G. Pellicci, Ruide Koh, Gurdyal S. Besra, Mandvi Bharadwaj, Dale I. Godfrey, James McCluskey & Jamie Rossjohn
doi:10.1038/nature05907
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Letters
宇宙：ヒペリオンのスポンジ状の外観
Hyperion's sponge-like appearance p50
P. C. Thomas, J. W. Armstrong, S. W. Asmar, J. A. Burns, T. Denk, B. Giese, P. Helfenstein, L. Iess, T. V. Johnson, A. McEwen, L. Nicolaisen, C. Porco, N. Rappaport, J. Richardson, L. Somenzi, P. Tortora, E. P. Turtle & J. Veverka
doi:10.1038/nature05779
宇宙：ヒペリオンの表面組成
Surface composition of Hyperion p54
D. P. Cruikshank, J. B. Dalton, C. M. Dalle Ore, J. Bauer, K. Stephan, G. Filacchione, A. R. Hendrix, C. J. Hansen, A. Coradini, P. Cerroni, F. Tosi, F. Capaccioni, R. Jaumann, B. J. Buratti, R. N. Clark, R. H. Brown, R. M. Nelson, T. B. McCord, K. H. Baines, P. D. Nicholson, C. Sotin, A. W. Meyer, G. Bellucci, M. Combes, J.-P. Bibring, Y. Langevin, B. Sicardy, D. L. Matson, V. Formisano, P. Drossart & V. Mennella
doi:10.1038/nature05948
物理：金属表面に生じる低エネルギー音響プラズモン
Low-energy acoustic plasmons at metal surfaces p57
Bogdan Diaconescu, Karsten Pohl, Luca Vattuone, Letizia Savio, Philip Hofmann, Vyacheslav M. Silkin, Jose M. Pitarke, Eugene V. Chulkov, Pedro M. Echenique, Daniel Farías & Mario Rocca
doi:10.1038/nature05975
宇宙：層状ケイ酸塩の熱力学的性質から明らかになった火星初期の地球化学的環境
Early geochemical environment of Mars as determined from thermodynamics of phyllosilicates p60
Vincent Chevrier, Francois Poulet & Jean-Pierre Bibring
doi:10.1038/nature05961
進化：相互擬態種は防御能に差がある場合にも相利的関係にある
Co-mimics have a mutualistic relationship despite unequal defences p64
Hannah M. Rowland, Eira Ihalainen, Leena Lindström, Johanna Mappes & Michael P. Speed
doi:10.1038/nature05899
神経：FIG4の変異が、pale tremorマウスとCMT4Jをもつ患者の神経変性の原因となる
Mutation of FIG4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J p68
Clement Y. Chow, Yanling Zhang, James J. Dowling, Natsuko Jin, Maja Adamska, Kensuke Shiga, Kinga Szigeti, Michael E. Shy, Jun Li, Xuebao Zhang, James R. Lupski, Lois S. Weisman & Miriam H. Meisler
doi:10.1038/nature05876
神経：新規な神経栄養因子CDNFはin vivoで中脳のドーパミンニューロンを保護し、救済する
Novel neurotrophic factor CDNF protects and rescues midbrain dopamine neurons in vivo p73
Päivi Lindholm, Merja H. Voutilainen, Juha Laurén, Johan Peränen, Veli-Matti Leppänen, Jaan-Olle Andressoo, Maria Lindahl, Sanna Janhunen, Nisse Kalkkinen, Tõnis Timmusk, Raimo K. Tuominen & Mart Saarma
doi:10.1038/nature05957
日本語要約 | Full Text | PDF (1,287K) | Supplementary information
生理：TRICチャネルは細胞内ストアのCa2+ハンドリングに必須である
TRIC channels are essential for Ca2+ handling in intracellular stores p78
Masayuki Yazawa, Christopher Ferrante, Jue Feng, Kazuhiro Mio, Toshihiko Ogura, Miao Zhang, Pei-Hui Lin, Zui Pan, Shinji Komazaki, Kazuhiro Kato, Miyuki Nishi, Xiaoli Zhao, Noah Weisleder, Chikara Sato, Jianjie Ma & Hiroshi Takeshima
doi:10.1038/nature05928
日本語要約 | Full Text | PDF (1,189K) | Supplementary information
細胞：Droshaによるプロセシングを回避するイントロン性マイクロRNA前駆体
Intronic microRNA precursors that bypass Drosha processing p83
J. Graham Ruby, Calvin H. Jan & David P. Bartel
doi:10.1038/nature05983
細胞：ヒストンデメチラーゼJMJD2Aの結晶構造が明らかにする基質特異性の基盤
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity p87
Stanley S. Ng, Kathryn L. Kavanagh, Michael A. McDonough, Danica Butler, Ewa S. Pilka, Benoit M. R. Lienard, James E. Bray, Pavel Savitsky, Opher Gileadi, Frank von Delft, Nathan R. Rose, John Offer, Johanna C. Scheinost, Tomasz Borowski, Michael Sundstrom, Christopher J. Schofield & Udo Oppermann
doi:10.1038/nature05971
日本語要約 | Full Text | PDF (1,029K) | Supplementary information
細胞：フェレドキシン-チオレドキシン還元酵素の反応経路に沿った構造スナップショット
Structural snapshots along the reaction pathway of ferredoxin–thioredoxin reductase p92
Shaodong Dai, Rosmarie Friemann, Dominique A. Glauser, Florence Bourquin, Wanda Manieri, Peter Schürmann & Hans Eklund
doi:10.1038/nature05937
日本語要約 | Full Text | PDF (1,756K) | Supplementary information
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Special Reports
Highlights
Naturejobs
ProspectProspects p97
Getting under-represented groups into science is still a work in progress.
Gene Russo
doi:10.1038/nj7149-097a
Special Reports
Beyond the glass ceiling p98
Women and under-represented minorities are earning historically high numbers of science doctorates in the United States. So why aren't they making it to the professorial ranks? Kendall Powell investigates.
Kendall Powell
doi:10.1038/nj7149-098a
Closing the gender gap p101
Across Europe, women in science are typically outnumbered by men at every level. Magdalena Wutte explores how institutions, networking organizations and women themselves can help correct the imbalance.
Magdalena Wutte
doi:10.1038/nj7149-101a
Highlights
Opportunities: The National Institutes of Health
doi:10.1038/nj0164
