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Nature 447, 1130-1134 (6 June 2007) | doi:10.1038/nature05939;
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A microRNA component of the p53 tumour suppressor network
A global decrease in microRNA (miRNA) levels is often observed in human cancers, indicating that small RNAs may have an intrinsic function in tumour suppression. To identify miRNA components of tumour suppressor pathways, we compared miRNA expression profiles of wild-type and p53-deficient cells.
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Abstract
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