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Editorials

All for one... p1031

Many medium-sized university departments feel they are engaged in an unequal struggle against larger and more-entrenched rivals. But there is a way in which they can fight back.

doi:10.1038/4471031a


Meanings of 'life' p1031

Synthetic biology provides a welcome antidote to chronic vitalism.

doi:10.1038/4471031b


Electric skies? p1032

How to navigate a flight path to greener air travel.

doi:10.1038/4471032a


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Research Highlights

Research highlights p1034

doi:10.1038/4471034a


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News

Cancer atlas maps out sample worries p1036

Initial wobbles show importance of quality control.

Erika Check

doi:10.1038/4471036a


Geophysicists combine forces p1037

Fresh drive to get data online for all.

Rex Dalton

doi:10.1038/4471037a


Graphic detail: Gas exchange: CO2 emissions 1990–2006 p1038

doi:10.1038/4471038a


Darfur's climate roots challenged p1038

Experts criticize UN view of Sudan conflict

Declan Butler

doi:10.1038/4471038b


Treaty caution on plankton plans p1039

Official concern voiced over iron fertilization of seas.

Mark Schrope

doi:10.1038/4471039a


Sidelines p1039

doi:10.1038/4471039b


Circumcision for HIV needs follow-up p1040

Worries about behaviour change require further research.

Declan Butler & Lucy Odling-Smee

doi:10.1038/4471040a


Plan for bomb design falters p1041

Congress gets cold feet over next generation nuke.

Geoff Brumfiel

doi:10.1038/4471041a


Uganda hosts banana trial p1042

Genetic modifications aim to beat fungal infection.

Anne Dauwers

doi:10.1038/4471042a


News in brief p1043

doi:10.1038/4471043a


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Business

Contest puts brakes on carbon capture p1044

As a BP project to capture carbon dioxide from a power station bites the dust, supporters argue that a major opportunity for Britain has been lost. Andrea Chipman reports.

doi:10.1038/4471044a


In brief p1045

doi:10.1038/4471045a


Market watch p1045

Colin Macilwain

doi:10.1038/4471045b


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News Features

Renewable energy: Energy-Go-Round p1046

How did a little Spanish province become one of the world's wind-energy giants? Daemon Fairless reports.

doi:10.1038/4471046a


Passive smoking: Out from the haze p1049

Smoking was banned in Californian bars a decade ago, and this week England follows suit. But Kris Novak finds that epidemiologists are still arguing about the effects of second-hand smoke.

doi:10.1038/4471049a

See also: Editor's summary


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Correspondence

Researchers fight poaching with presence, not guns p1052

Gottfried Hohmann

doi:10.1038/4471052a


Estimating the cost of climate change p1052

Richard Tol

doi:10.1038/4471052b


Not so sunny view of the events in Arizona p1052

Carl Djerassi

doi:10.1038/4471052c


Why are people reluctant to join in open review? p1052

Shi V. Liu

doi:10.1038/4471052d


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Commentary

Tony Blair's era: good news, bad news p1053

As Gordon Brown becomes Britain's prime minister, Robert May highlights some critical challenges in the continuing support of science.

doi:10.1038/4471053a

See also: Editor's summary


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Books and Arts

Falling over the edge p1055

Claims that an intelligent designer is needed to explain evolution of complex systems are deeply flawed.

Kenneth R. Miller reviews The Edge of Evolution: The Search for the Limits of Darwinism by Michael Behe

doi:10.1038/4471055a


Exhibition: A Wellcome addition p1056

Sara Abdulla reviews The Wellcome Collection

doi:10.1038/4471056a


Life drawing p1057

doi:10.1038/4471057a


A better way of thinking? p1057

Frances Cairncross reviews The Soulful Science: What Economists Really Do and Why It Matters by Diane Coyle

doi:10.1038/4471057b


Science in culture: The clever cone p1058

A new planetarium for the Royal Observatory in Greenwich.

Martin Kemp

doi:10.1038/4471058a

See also: Editor's summary


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News and Views

Neurophysiology: Stressful pacemaking p1059

In Parkinson's disease, dopamine-secreting neurons die — perhaps because unrelenting calcium entry during spontaneous electrical activity puts them under unusual pressure.

Bruce P. Bean

doi:10.1038/4471059a

See also: Editor's summary


Earth science: Silicon-enhanced core p1060

What elements, besides iron, make up Earth's core? Discrepancies in the isotopic ratios found in rocks from Earth's mantle and in undisturbed meteoritic material indicate strongly that one answer is silicon.

Tim Elliott

doi:10.1038/4471060a

See also: Editor's summary


Neurobiology: The currency of guessing p1061

Vanilla or chocolate? Fight or flight? A career in academia or in industry? The neural processes of probabilistic decision-making provide clues about the 'common currency' through which decisions are made.

Paul Cisek

doi:10.1038/4471061a

See also: Editor's summary


50 & 100 Years Ago p1062

doi:10.1038/4471062a


Astronomy: A new molecular factory p1063

Carbon-rich stars are known to be prolific producers of molecules. Against expectations, astronomers have identified an old, oxygen-rich star that can also synthesize a chemically varied molecular cocktail.

Sun Kwok

doi:10.1038/4471063a

See also: Editor's summary


Robert Cahn (1924–2007) p1063

doi:10.1038/4471063b


Obituary: Bohdan Paczyn acuteski (1940–2007) p1064

Guiding light in astrophysics.

Bruce T. Draine & Jeremiah P. Ostriker

doi:10.1038/4471064a


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News and Views Q&A

Materials Science: Nanotube composites p1066

A carbon revolution has occurred — carbon atoms can be coaxed into several topologies to make materials with unique properties. Nanotubes are the vanguard of this innovation, and are on the cusp of commercial exploitation as the multifunctional components of the next generation of composite materials.

Pulickel M. Ajayan & James M. Tour

doi:10.1038/4471066a

See also: Editor's summary


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Articles

Isotopic portrayal of the Earth's upper mantle flow field p1069

Christine M. Meyzen, Janne Blichert-Toft, John N. Ludden, Eric Humler, Catherine Mével & Francis Albarède

doi:10.1038/nature05920


Probabilistic reasoning by neurons p1075

Tianming Yang & Michael N. Shadlen

doi:10.1038/nature05852

See also: Editor's summary | News and Views by Cisek


'Rejuvenation' protects neurons in mouse models of Parkinson's disease p1081

C. Savio Chan, Jaime N. Guzman, Ema Ilijic, Jeff N. Mercer, Caroline Rick, Tatiana Tkatch, Gloria E. Meredith & D. James Surmeier

doi:10.1038/nature05865

See also: Editor's summary | News and Views by Bean


Genome-wide association study identifies novel breast cancer susceptibility loci p1087

Douglas F. Easton, Karen A. Pooley, Alison M. Dunning, Paul D. P. Pharoah, Deborah Thompson, Dennis G. Ballinger, Jeffery P. Struewing, Jonathan Morrison, Helen Field, Robert Luben, Nicholas Wareham, Shahana Ahmed, Catherine S. Healey, Richard BowmanThe SEARCH collaborators and , Kerstin B. Meyer, Christopher A. Haiman, Laurence K. Kolonel, Brian E. Henderson, Loic Le Marchand, Paul Brennan, Suleeporn Sangrajrang, Valerie Gaborieau, Fabrice Odefrey, Chen-Yang Shen, Pei-Ei Wu, Hui-Chun Wang, Diana Eccles, D. Gareth Evans, Julian Peto, Olivia Fletcher, Nichola Johnson, Sheila Seal, Michael R. Stratton, Nazneen Rahman, Georgia Chenevix-Trench, Stig E. Bojesen, Børge G. Nordestgaard, Christen K. Axelsson, Montserrat Garcia-Closas, Louise Brinton, Stephen Chanock, Jolanta Lissowska, Beata Peplonska, Heli Nevanlinna, Rainer Fagerholm, Hannaleena Eerola, Daehee Kang, Keun-Young Yoo, Dong-Young Noh, Sei-Hyun Ahn, David J. Hunter, Susan E. Hankinson, David G. Cox, Per Hall, Sara Wedren, Jianjun Liu, Yen-Ling Low, Natalia Bogdanova, Peter Schürmann, Thilo Dörk, Rob A. E. M. Tollenaar, Catharina E. Jacobi, Peter Devilee, Jan G. M. Klijn, Alice J. Sigurdson, Michele M. Doody, Bruce H. Alexander, Jinghui Zhang, Angela Cox, Ian W. Brock, Gordon MacPherson, Malcolm W. R. Reed, Fergus J. Couch, Ellen L. Goode, Janet E. Olson, Hanne Meijers-Heijboer, Ans van den Ouweland, André Uitterlinden, Fernando Rivadeneira, Roger L. Milne, Gloria Ribas, Anna Gonzalez-Neira, Javier Benitez, John L. Hopper, Margaret McCredie, Melissa Southey, Graham G. Giles, Chris Schroen, Christina Justenhoven, Hiltrud Brauch, Ute Hamann, Yon-Dschun Ko, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing ChenkConFab and AOCS Management Group and , Arto Mannermaa, Veli-Matti Kosma, Vesa Kataja, Jaana Hartikainen, Nicholas E. Day, David R. Cox & Bruce A. J. Ponder

doi:10.1038/nature05887

See also: Editor's summary


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Letters

Chemical complexity in the winds of the oxygen-rich supergiant star VY Canis Majoris p1094

L. M. Ziurys, S. N. Milam, A. J. Apponi & N. J. Woolf

doi:10.1038/nature05905

See also: Editor's summary | News and Views by Kwok


Tunable nanowire nonlinear optical probe p1098

Yuri Nakayama, Peter J. Pauzauskie, Aleksandra Radenovic, Robert M. Onorato, Richard J. Saykally, Jan Liphardt & Peidong Yang

doi:10.1038/nature05921

See also: Editor's summary


Silicon in the Earth's core p1102

R. Bastian Georg, Alex N. Halliday, Edwin A. Schauble & Ben C. Reynolds

doi:10.1038/nature05927

See also: Editor's summary | News and Views by Elliott


Sexually antagonistic genetic variation for fitness in red deer p1107

Katharina Foerster, Tim Coulson, Ben C. Sheldon, Josephine M. Pemberton, Tim H. Clutton-Brock & Loeske E. B. Kruuk

doi:10.1038/nature05912

See also: Editor's summary


Lateral habenula as a source of negative reward signals in dopamine neurons p1111

Masayuki Matsumoto & Okihide Hikosaka

doi:10.1038/nature05860

See also: Editor's summary


Macrophage-specific PPARbold gamma controls alternative activation and improves insulin resistance p1116

Justin I. Odegaard, Roberto R. Ricardo-Gonzalez, Matthew H. Goforth, Christine R. Morel, Vidya Subramanian, Lata Mukundan, Alex Red Eagle, Divya Vats, Frank Brombacher, Anthony W. Ferrante & Ajay Chawla

doi:10.1038/nature05894


Ambra1 regulates autophagy and development of the nervous system p1121

Gian Maria Fimia, Anastassia Stoykova, Alessandra Romagnoli, Luigi Giunta, Sabrina Di Bartolomeo, Roberta Nardacci, Marco Corazzari, Claudia Fuoco, Ahmet Ucar, Peter Schwartz, Peter Gruss, Mauro Piacentini, Kamal Chowdhury & Francesco Cecconi

doi:10.1038/nature05925


miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii p1126

Attila Molnár, Frank Schwach, David J. Studholme, Eva C. Thuenemann & David C. Baulcombe

doi:10.1038/nature05903

See also: Editor's summary


A microRNA component of the p53 tumour suppressor network p1130

Lin He, Xingyue He, Lee P. Lim, Elisa de Stanchina, Zhenyu Xuan, Yu Liang, Wen Xue, Lars Zender, Jill Magnus, Dana Ridzon, Aimee L. Jackson, Peter S. Linsley, Caifu Chen, Scott W. Lowe, Michele A. Cleary & Gregory J. Hannon

doi:10.1038/nature05939

See also: Editor's summary


Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging p1135

Jianping Jin, Xue Li, Steven P. Gygi & J. Wade Harper

doi:10.1038/nature05902


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Naturejobs

Prospect

Rankings are flawed, but are they a worthwhile tool nonetheless? p1139

Gene Russo

doi:10.1038/nj7148-1139a


Career Views

Thomas Mason, Director, Oak Ridge National Laboratory, Oak Ridge, Tennessee p1140

New director at Oak Ridge National Laboratory

Virginia Gewin

doi:10.1038/nj7148-1140a


Making contacts online p1140

Online networking sites for science

Fabio Fais

doi:10.1038/nj7148-1140b


The final push p1140

Preparing for a work hiatus

Moira Sheehan

doi:10.1038/nj7148-1140c


Recruiters

Taking on that first faculty job p1142

You know the science, but there's plenty else to consider.

David Burgess

doi:10.1038/nj7148-1142a


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