Table of contents
Volume 447 Number 7148 pp1031-1142
(this content only available online) indicates content that is available online only
Editorials
All for one... p1031
Many medium-sized university departments feel they are engaged in an unequal struggle against larger and more-entrenched rivals. But there is a way in which they can fight back.
doi:10.1038/4471031a
Meanings of 'life' p1031
Synthetic biology provides a welcome antidote to chronic vitalism.
doi:10.1038/4471031b
Electric skies? p1032
How to navigate a flight path to greener air travel.
doi:10.1038/4471032a
News
Cancer atlas maps out sample worries p1036
Initial wobbles show importance of quality control.
Erika Check
doi:10.1038/4471036a
Geophysicists combine forces p1037
Fresh drive to get data online for all.
Rex Dalton
doi:10.1038/4471037a
Graphic detail: Gas exchange: CO2 emissions 1990–2006 p1038
doi:10.1038/4471038a
Darfur's climate roots challenged p1038
Experts criticize UN view of Sudan conflict
Declan Butler
doi:10.1038/4471038b
Treaty caution on plankton plans p1039
Official concern voiced over iron fertilization of seas.
Mark Schrope
doi:10.1038/4471039a
Sidelines p1039
doi:10.1038/4471039b
Circumcision for HIV needs follow-up p1040
Worries about behaviour change require further research.
Declan Butler & Lucy Odling-Smee
doi:10.1038/4471040a
Plan for bomb design falters p1041
Congress gets cold feet over next generation nuke.
Geoff Brumfiel
doi:10.1038/4471041a
Uganda hosts banana trial p1042
Genetic modifications aim to beat fungal infection.
Anne Dauwers
doi:10.1038/4471042a
Business
Contest puts brakes on carbon capture p1044
As a BP project to capture carbon dioxide from a power station bites the dust, supporters argue that a major opportunity for Britain has been lost. Andrea Chipman reports.
doi:10.1038/4471044a
In brief p1045
doi:10.1038/4471045a
Market watch p1045
Colin Macilwain
doi:10.1038/4471045b
News Features
Renewable energy: Energy-Go-Round p1046
How did a little Spanish province become one of the world's wind-energy giants? Daemon Fairless reports.
doi:10.1038/4471046a
Passive smoking: Out from the haze p1049
Smoking was banned in Californian bars a decade ago, and this week England follows suit. But Kris Novak finds that epidemiologists are still arguing about the effects of second-hand smoke.
doi:10.1038/4471049a
See also: Editor's summary
Correspondence
Researchers fight poaching with presence, not guns p1052
Gottfried Hohmann
doi:10.1038/4471052a
Estimating the cost of climate change p1052
Richard Tol
doi:10.1038/4471052b
Not so sunny view of the events in Arizona p1052
Carl Djerassi
doi:10.1038/4471052c
Why are people reluctant to join in open review? p1052
Shi V. Liu
doi:10.1038/4471052d
Commentary
Tony Blair's era: good news, bad news p1053
As Gordon Brown becomes Britain's prime minister, Robert May highlights some critical challenges in the continuing support of science.
doi:10.1038/4471053a
See also: Editor's summary
Books and Arts
Falling over the edge p1055
Claims that an intelligent designer is needed to explain evolution of complex systems are deeply flawed.
Kenneth R. Miller reviews The Edge of Evolution: The Search for the Limits of Darwinism by Michael Behe
doi:10.1038/4471055a
Exhibition: A Wellcome addition p1056
Sara Abdulla reviews The Wellcome Collection
doi:10.1038/4471056a
Life drawing p1057
doi:10.1038/4471057a
A better way of thinking? p1057
Frances Cairncross reviews The Soulful Science: What Economists Really Do and Why It Matters by Diane Coyle
doi:10.1038/4471057b
Science in culture: The clever cone p1058
A new planetarium for the Royal Observatory in Greenwich.
Martin Kemp
doi:10.1038/4471058a
See also: Editor's summary
News and Views
Neurophysiology: Stressful pacemaking p1059
In Parkinson's disease, dopamine-secreting neurons die — perhaps because unrelenting calcium entry during spontaneous electrical activity puts them under unusual pressure.
Bruce P. Bean
doi:10.1038/4471059a
See also: Editor's summary
Earth science: Silicon-enhanced core p1060
What elements, besides iron, make up Earth's core? Discrepancies in the isotopic ratios found in rocks from Earth's mantle and in undisturbed meteoritic material indicate strongly that one answer is silicon.
Tim Elliott
doi:10.1038/4471060a
See also: Editor's summary
Neurobiology: The currency of guessing p1061
Vanilla or chocolate? Fight or flight? A career in academia or in industry? The neural processes of probabilistic decision-making provide clues about the 'common currency' through which decisions are made.
Paul Cisek
doi:10.1038/4471061a
See also: Editor's summary
50 & 100 Years Ago p1062
doi:10.1038/4471062a
Astronomy: A new molecular factory p1063
Carbon-rich stars are known to be prolific producers of molecules. Against expectations, astronomers have identified an old, oxygen-rich star that can also synthesize a chemically varied molecular cocktail.
Sun Kwok
doi:10.1038/4471063a
See also: Editor's summary
Robert Cahn (1924–2007) p1063
doi:10.1038/4471063b
Obituary: Bohdan Paczy
ski (1940–2007) p1064
Guiding light in astrophysics.
Bruce T. Draine & Jeremiah P. Ostriker
doi:10.1038/4471064a
News and Views Q&A
Materials Science: Nanotube composites p1066
A carbon revolution has occurred — carbon atoms can be coaxed into several topologies to make materials with unique properties. Nanotubes are the vanguard of this innovation, and are on the cusp of commercial exploitation as the multifunctional components of the next generation of composite materials.
Pulickel M. Ajayan & James M. Tour
doi:10.1038/4471066a
See also: Editor's summary
Articles
Isotopic portrayal of the Earth's upper mantle flow field p1069
Christine M. Meyzen, Janne Blichert-Toft, John N. Ludden, Eric Humler, Catherine Mével & Francis Albarède
doi:10.1038/nature05920
Abstract | Full Text | PDF (911K) | Supplementary information
Probabilistic reasoning by neurons p1075
Tianming Yang & Michael N. Shadlen
doi:10.1038/nature05852
Abstract | Full Text | PDF (437K) | Supplementary information
See also: Editor's summary | News and Views by Cisek
'Rejuvenation' protects neurons in mouse models of Parkinson's disease p1081
C. Savio Chan, Jaime N. Guzman, Ema Ilijic, Jeff N. Mercer, Caroline Rick, Tatiana Tkatch, Gloria E. Meredith & D. James Surmeier
doi:10.1038/nature05865
Abstract | Full Text | PDF (1,458K) | Supplementary information
See also: Editor's summary | News and Views by Bean
Genome-wide association study identifies novel breast cancer susceptibility loci p1087
Douglas F. Easton, Karen A. Pooley, Alison M. Dunning, Paul D. P. Pharoah, Deborah Thompson, Dennis G. Ballinger, Jeffery P. Struewing, Jonathan Morrison, Helen Field, Robert Luben, Nicholas Wareham, Shahana Ahmed, Catherine S. Healey, Richard BowmanThe SEARCH collaborators and , Kerstin B. Meyer, Christopher A. Haiman, Laurence K. Kolonel, Brian E. Henderson, Loic Le Marchand, Paul Brennan, Suleeporn Sangrajrang, Valerie Gaborieau, Fabrice Odefrey, Chen-Yang Shen, Pei-Ei Wu, Hui-Chun Wang, Diana Eccles, D. Gareth Evans, Julian Peto, Olivia Fletcher, Nichola Johnson, Sheila Seal, Michael R. Stratton, Nazneen Rahman, Georgia Chenevix-Trench, Stig E. Bojesen, Børge G. Nordestgaard, Christen K. Axelsson, Montserrat Garcia-Closas, Louise Brinton, Stephen Chanock, Jolanta Lissowska, Beata Peplonska, Heli Nevanlinna, Rainer Fagerholm, Hannaleena Eerola, Daehee Kang, Keun-Young Yoo, Dong-Young Noh, Sei-Hyun Ahn, David J. Hunter, Susan E. Hankinson, David G. Cox, Per Hall, Sara Wedren, Jianjun Liu, Yen-Ling Low, Natalia Bogdanova, Peter Schürmann, Thilo Dörk, Rob A. E. M. Tollenaar, Catharina E. Jacobi, Peter Devilee, Jan G. M. Klijn, Alice J. Sigurdson, Michele M. Doody, Bruce H. Alexander, Jinghui Zhang, Angela Cox, Ian W. Brock, Gordon MacPherson, Malcolm W. R. Reed, Fergus J. Couch, Ellen L. Goode, Janet E. Olson, Hanne Meijers-Heijboer, Ans van den Ouweland, André Uitterlinden, Fernando Rivadeneira, Roger L. Milne, Gloria Ribas, Anna Gonzalez-Neira, Javier Benitez, John L. Hopper, Margaret McCredie, Melissa Southey, Graham G. Giles, Chris Schroen, Christina Justenhoven, Hiltrud Brauch, Ute Hamann, Yon-Dschun Ko, Amanda B. Spurdle, Jonathan Beesley, Xiaoqing ChenkConFab and AOCS Management Group and , Arto Mannermaa, Veli-Matti Kosma, Vesa Kataja, Jaana Hartikainen, Nicholas E. Day, David R. Cox & Bruce A. J. Ponder
doi:10.1038/nature05887
Abstract | Full Text | PDF (839K) | Supplementary information
See also: Editor's summary
Letters
Chemical complexity in the winds of the oxygen-rich supergiant star VY Canis Majoris p1094
L. M. Ziurys, S. N. Milam, A. J. Apponi & N. J. Woolf
doi:10.1038/nature05905
First paragraph | Full Text | PDF (281K) | Supplementary information
See also: Editor's summary | News and Views by Kwok
Tunable nanowire nonlinear optical probe p1098
Yuri Nakayama, Peter J. Pauzauskie, Aleksandra Radenovic, Robert M. Onorato, Richard J. Saykally, Jan Liphardt & Peidong Yang
doi:10.1038/nature05921
First paragraph | Full Text | PDF (1,524K) | Supplementary information
See also: Editor's summary
Silicon in the Earth's core p1102
R. Bastian Georg, Alex N. Halliday, Edwin A. Schauble & Ben C. Reynolds
doi:10.1038/nature05927
First paragraph | Full Text | PDF (260K) | Supplementary information
See also: Editor's summary | News and Views by Elliott
Sexually antagonistic genetic variation for fitness in red deer p1107
Katharina Foerster, Tim Coulson, Ben C. Sheldon, Josephine M. Pemberton, Tim H. Clutton-Brock & Loeske E. B. Kruuk
doi:10.1038/nature05912
First paragraph | Full Text | PDF (336K) | Supplementary information
See also: Editor's summary
Lateral habenula as a source of negative reward signals in dopamine neurons p1111
Masayuki Matsumoto & Okihide Hikosaka
doi:10.1038/nature05860
First paragraph | Full Text | PDF (627K) | Supplementary information
See also: Editor's summary
Macrophage-specific PPAR
controls alternative activation and improves insulin resistance p1116
Justin I. Odegaard, Roberto R. Ricardo-Gonzalez, Matthew H. Goforth, Christine R. Morel, Vidya Subramanian, Lata Mukundan, Alex Red Eagle, Divya Vats, Frank Brombacher, Anthony W. Ferrante & Ajay Chawla
doi:10.1038/nature05894
First paragraph | Full Text | PDF (406K) | Supplementary information
Ambra1 regulates autophagy and development of the nervous system p1121
Gian Maria Fimia, Anastassia Stoykova, Alessandra Romagnoli, Luigi Giunta, Sabrina Di Bartolomeo, Roberta Nardacci, Marco Corazzari, Claudia Fuoco, Ahmet Ucar, Peter Schwartz, Peter Gruss, Mauro Piacentini, Kamal Chowdhury & Francesco Cecconi
doi:10.1038/nature05925
First paragraph | Full Text | PDF (1,379K) | Supplementary information
miRNAs control gene expression in the single-cell alga Chlamydomonas reinhardtii p1126
Attila Molnár, Frank Schwach, David J. Studholme, Eva C. Thuenemann & David C. Baulcombe
doi:10.1038/nature05903
First paragraph | Full Text | PDF (719K) | Supplementary information
See also: Editor's summary
A microRNA component of the p53 tumour suppressor network p1130
Lin He, Xingyue He, Lee P. Lim, Elisa de Stanchina, Zhenyu Xuan, Yu Liang, Wen Xue, Lars Zender, Jill Magnus, Dana Ridzon, Aimee L. Jackson, Peter S. Linsley, Caifu Chen, Scott W. Lowe, Michele A. Cleary & Gregory J. Hannon
doi:10.1038/nature05939
First paragraph | Full Text | PDF (448K) | Supplementary information
See also: Editor's summary
Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging p1135
Jianping Jin, Xue Li, Steven P. Gygi & J. Wade Harper
doi:10.1038/nature05902
First paragraph | Full Text | PDF (858K) | Supplementary information
Naturejobs
ProspectRankings are flawed, but are they a worthwhile tool nonetheless? p1139
Gene Russo
doi:10.1038/nj7148-1139a
Career Views
Thomas Mason, Director, Oak Ridge National Laboratory, Oak Ridge, Tennessee p1140
New director at Oak Ridge National Laboratory
Virginia Gewin
doi:10.1038/nj7148-1140a
Making contacts online p1140
Online networking sites for science
Fabio Fais
doi:10.1038/nj7148-1140b
The final push p1140
Preparing for a work hiatus
Moira Sheehan
doi:10.1038/nj7148-1140c
Recruiters
Taking on that first faculty job p1142
You know the science, but there's plenty else to consider.
David Burgess
doi:10.1038/nj7148-1142a