Figures and Tables

From the following article:

Base-excision repair of oxidative DNA damage

Sheila S. David, Valerie L. O'Shea & Sucharita Kundu

Nature 447, 941-950(21 June 2007)

doi:10.1038/nature05978

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Figure 1

Short-patch BER pathway for 8-oxoG.

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Figure 2

Structures of 8-oxoG-containing base pairs and of several nucleosides of guanine oxidation products.

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Figure 3

Recognition of 8-oxoG by OGG1 observed in the LRC of OGG1 with 8-oxoGdotC-containing duplexes.

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Figure 4

The LRCs of OGG1 and MutM with non-specific complexes (normal base pairs).

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Figure 5

The 8-oxoG lesion search process.

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Figure 6

Germline mutations observed in MUTYH in individuals with MUTYH-associated polyposis.

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