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Nature 447, 782-783 (14 June 2007) | doi:10.1038/447782a; Published online 13 June 2007

Genomics: Encyclopaedia of humble DNA

John M. Greally1

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Researchers of the ENCODE consortium have analysed 1% of the human genome. Their findings bring us a step closer to understanding the role of the vast amount of obscure DNA that does not function as genes.

We usually think of the functional sequences in the genome solely in terms of genes, the sequences transcribed to messenger RNA to generate proteins. This perception is really the result of effective publicity by the genes, who take all of the credit even though their function is basically limited to communicating genomic information to the outside world.