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From the following article:

MicroRNA silencing through RISC recruitment of eIF6

Thimmaiah P. Chendrimada, Kenneth J. Finn, Xinjun Ji, David Baillat, Richard I. Gregory, Stephen A. Liebhaber, Amy E. Pasquinelli & Ramin Shiekhattar

Nature 447, 823-828(14 July 2007)

doi:10.1038/nature05841

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Biochemical and functional analysis of eIF6 in the miRNA pathway.

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Figure 2

Impact of eIF6 depletion on let-7-responsive reporter mRNA levels and on cellular polysome profiles.

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Figure 3

Depletion of eif-6 disrupts regulation of protein levels of lin-4 miRNA endogenous targets.

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Figure 4

RNAi of eif-6 results in misregulation of lin-14 and lin-28 target mRNA levels.

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Figure 5

Depletion of EIF-6 during C. elegans larval development.

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