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TY  - JOUR
AU  - Weissman, I. L.
TI  - Stem cells: units of development, units of regeneration, and units in evolution
JA  - Cell
PY  - 2000///
VL  - 100
SP  - 157
EP  - 168
M3  - 10.1016/S0092-8674(00)81692-X
N1  - 10.1016/S0092-8674(00)81692-X
UR  - http://dx.doi.org/10.1016/S0092-8674(00)81692-X
ER  -

TY  - JOUR
AU  - Park, Y.
AU  - Gerson, S. L.
TI  - DNA repair defects in stem cell function and aging
JA  - Annu. Rev. Med.
PY  - 2005///
VL  - 56
SP  - 495
EP  - 508
M3  - 10.1146/annurev.med.56.082103.104546
N1  - 10.1146/annurev.med.56.082103.104546
UR  - http://dx.doi.org/10.1146/annurev.med.56.082103.104546
ER  -

TY  - JOUR
AU  - Wang, Y.
AU  - Schulte, B. A.
AU  - LaRue, A. C.
AU  - Ogawa, M.
AU  - Zhou, D.
TI  - Total body irradiation selectively induces murine hematopoietic stem cell senescence
JA  - Blood
PY  - 2006///
VL  - 107
SP  - 358
EP  - 366
M3  - 10.1182/blood-2005-04-1418
N1  - 10.1182/blood-2005-04-1418
UR  - http://dx.doi.org/10.1182/blood-2005-04-1418
ER  -

TY  - JOUR
AU  - Khanna, K. K.
AU  - Jackson, S. P.
TI  - DNA double-strand breaks: signaling, repair and the cancer connection
JA  - Nature Genet.
PY  - 2001///
VL  - 27
SP  - 247
EP  - 254
M3  - 10.1038/85798
N1  - 10.1038/85798
UR  - http://dx.doi.org/10.1038/85798
ER  -

TY  - JOUR
AU  - Karanjawala, Z. E.
AU  - Murphy, N.
AU  - Hinton, D. R.
AU  - Hsieh, C. L.
AU  - Lieber, M. R.
TI  - Oxygen metabolism causes chromosome breaks and is associated with the neuronal apoptosis observed in DNA double-strand break repair mutants
JA  - Curr. Biol.
PY  - 2002///
VL  - 12
SP  - 397
EP  - 402
M3  - 10.1016/S0960-9822(02)00684-X
N1  - 10.1016/S0960-9822(02)00684-X
UR  - http://dx.doi.org/10.1016/S0960-9822(02)00684-X
ER  -

TY  - JOUR
AU  - Weterings, E.
AU  - van Gent, D. C.
TI  - The mechanism of non-homologous end-joining: a synopsis of synapsis
JA  - DNA Repair (Amst.)
PY  - 2004///
VL  - 3
SP  - 1425
EP  - 1435
ER  -

TY  - JOUR
AU  - Lieber, M. R.
AU  - Ma, Y.
AU  - Pannicke, U.
AU  - Schwarz, K.
TI  - Mechanism and regulation of human non-homologous DNA end-joining
JA  - Nature Rev. Mol. Cell Biol.
PY  - 2003///
VL  - 4
SP  - 712
EP  - 720
M3  - 10.1038/nrm1202
N1  - 10.1038/nrm1202
UR  - http://dx.doi.org/10.1038/nrm1202
ER  -

TY  - JOUR
AU  - Ito, K.
TI  - Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
JA  - Nature
PY  - 2004///
VL  - 431
SP  - 997
EP  - 1002
M3  - 10.1038/nature02989
N1  - 10.1038/nature02989
UR  - http://dx.doi.org/10.1038/nature02989
ER  -

TY  - JOUR
AU  - Sedelnikova, O. A.
TI  - Senescing human cells and ageing mice accumulate DNA lesions with unrepairable double-strand breaks
JA  - Nature Cell Biol.
PY  - 2004///
VL  - 6
SP  - 168
EP  - 170
M3  - 10.1038/ncb1095
N1  - 10.1038/ncb1095
UR  - http://dx.doi.org/10.1038/ncb1095
ER  -

TY  - JOUR
AU  - Bender, C. F.
TI  - Cancer predisposition and hematopoietic failure in Rad50(S/S) mice
JA  - Genes Dev.
PY  - 2002///
VL  - 16
SP  - 2237
EP  - 2251
M3  - 10.1101/gad.1007902
N1  - 10.1101/gad.1007902
UR  - http://dx.doi.org/10.1101/gad.1007902
ER  -

TY  - JOUR
AU  - Dumble, M.
TI  - The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging
JA  - Blood
PY  - 2006///
VL  - 109
SP  - 1736
EP  - 1742
M3  - 10.1182/blood-2006-03-010413
N1  - 10.1182/blood-2006-03-010413
UR  - http://dx.doi.org/10.1182/blood-2006-03-010413
ER  -

TY  - JOUR
AU  - Buck, D.
TI  - Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly
JA  - Cell
PY  - 2006///
VL  - 124
SP  - 287
EP  - 299
M3  - 10.1016/j.cell.2005.12.030
N1  - 10.1016/j.cell.2005.12.030
UR  - http://dx.doi.org/10.1016/j.cell.2005.12.030
ER  -

TY  - JOUR
AU  - Ahnesorg, P.
AU  - Smith, P.
AU  - Jackson, S. P.
TI  - XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining
JA  - Cell
PY  - 2006///
VL  - 124
SP  - 301
EP  - 313
M3  - 10.1016/j.cell.2005.12.031
N1  - 10.1016/j.cell.2005.12.031
UR  - http://dx.doi.org/10.1016/j.cell.2005.12.031
ER  -

TY  - JOUR
AU  - Riballo, E.
TI  - A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to [ggr]-H2AX foci
JA  - Mol. Cell
PY  - 2004///
VL  - 16
SP  - 715
EP  - 724
M3  - 10.1016/j.molcel.2004.10.029
N1  - 10.1016/j.molcel.2004.10.029
UR  - http://dx.doi.org/10.1016/j.molcel.2004.10.029
ER  -

TY  - JOUR
AU  - Hsu, H. L.
AU  - Gilley, D.
AU  - Blackburn, E. H.
AU  - Chen, D. J.
TI  - Ku is associated with the telomere in mammals
JA  - Proc. Natl Acad. Sci. USA
PY  - 1999///
VL  - 96
SP  - 12454
EP  - 12458
M3  - 10.1073/pnas.96.22.12454
N1  - 10.1073/pnas.96.22.12454
UR  - http://dx.doi.org/10.1073/pnas.96.22.12454
ER  -

TY  - JOUR
AU  - d/'Adda di Fagagna, F.
TI  - Effects of DNA nonhomologous end-joining factors on telomere length and chromosomal stability in mammalian cells
JA  - Curr. Biol.
PY  - 2001///
VL  - 11
SP  - 1192
EP  - 1196
M3  - 10.1016/S0960-9822(01)00328-1
N1  - 10.1016/S0960-9822(01)00328-1
UR  - http://dx.doi.org/10.1016/S0960-9822(01)00328-1
ER  -

TY  - JOUR
AU  - Barnes, D. E.
AU  - Stamp, G.
AU  - Rosewell, I.
AU  - Denzel, A.
AU  - Lindahl, T.
TI  - Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
JA  - Curr. Biol.
PY  - 1998///
VL  - 8
SP  - 1395
EP  - 1398
M3  - 10.1016/S0960-9822(98)00021-9
N1  - 10.1016/S0960-9822(98)00021-9
UR  - http://dx.doi.org/10.1016/S0960-9822(98)00021-9
ER  -

TY  - JOUR
AU  - Frank, K. M.
TI  - Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
JA  - Nature
PY  - 1998///
VL  - 396
SP  - 173
EP  - 177
M3  - 10.1038/24172
N1  - 10.1038/24172
UR  - http://dx.doi.org/10.1038/24172
ER  -

TY  - JOUR
AU  - O/'Driscoll, M.
TI  - DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency
JA  - Mol. Cell
PY  - 2001///
VL  - 8
SP  - 1175
EP  - 1185
M3  - 10.1016/S1097-2765(01)00408-7
N1  - 10.1016/S1097-2765(01)00408-7
UR  - http://dx.doi.org/10.1016/S1097-2765(01)00408-7
ER  -

TY  - JOUR
AU  - Ben-Omran, T. I.
AU  - Cerosaletti, K.
AU  - Concannon, P.
AU  - Weitzman, S.
AU  - Nezarati, M. M.
TI  - A patient with mutations in DNA Ligase IV: clinical features and overlap with Nijmegen breakage syndrome
JA  - Am. J. Med. Genet. A.
PY  - 2005///
VL  - 137
SP  - 283
EP  - 287
ER  -

TY  - JOUR
AU  - van der Burg, M.
TI  - A new type of radiosensitive TBNK severe combined immunodeficiency caused by a LIG4 mutation
JA  - J. Clin. Invest.
PY  - 2006///
VL  - 116
SP  - 137
EP  - 145
M3  - 10.1172/JCI26121
N1  - 10.1172/JCI26121
UR  - http://dx.doi.org/10.1172/JCI26121
ER  -

TY  - JOUR
AU  - Enders, A.
TI  - A severe form of human combined immunodeficiency due to mutations in DNA ligase IV
JA  - J. Immunol.
PY  - 2006///
VL  - 176
SP  - 5060
EP  - 5068
ER  -

TY  - JOUR
AU  - Toita, N.
TI  - Epstein-Barr virus-associated B-cell lymphoma in a patient with DNA ligase IV (LIG4) syndrome
JA  - Am. J. Med. Genet. A
PY  - 2007///
VL  - 143
SP  - 742
EP  - 745
ER  -

TY  - JOUR
AU  - Gruhn, B.
TI  - Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure
JA  - Orphanet J. Rare Dis.
PY  - 2007///
VL  - 2
SP  - 5
M3  - 10.1186/1750-1172-2-5
N1  - 10.1186/1750-1172-2-5
UR  - http://dx.doi.org/10.1186/1750-1172-2-5
ER  -

TY  - JOUR
AU  - Sekiguchi, J. M.
AU  - Ferguson, D. O.
TI  - DNA double-strand break repair: a relentless hunt uncovers new prey
JA  - Cell
PY  - 2006///
VL  - 124
SP  - 260
EP  - 262
M3  - 10.1016/j.cell.2006.01.010
N1  - 10.1016/j.cell.2006.01.010
UR  - http://dx.doi.org/10.1016/j.cell.2006.01.010
ER  -

TY  - JOUR
AU  - Nelms, K. A.
AU  - Goodnow, C. C.
TI  - Genome-wide ENU mutagenesis to reveal immune regulators
JA  - Immunity
PY  - 2001///
VL  - 15
SP  - 409
EP  - 418
M3  - 10.1016/S1074-7613(01)00199-6
N1  - 10.1016/S1074-7613(01)00199-6
UR  - http://dx.doi.org/10.1016/S1074-7613(01)00199-6
ER  -

TY  - JOUR
AU  - Quwailid, M. M.
TI  - A gene-driven ENU-based approach to generating an allelic series in any gene
JA  - Mamm. Genome
PY  - 2004///
VL  - 15
SP  - 585
EP  - 591
M3  - 10.1007/s00335-004-2379-z
N1  - 10.1007/s00335-004-2379-z
UR  - http://dx.doi.org/10.1007/s00335-004-2379-z
ER  -

TY  - JOUR
AU  - Grawunder, U.
TI  - Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
JA  - Nature
PY  - 1997///
VL  - 388
SP  - 492
EP  - 495
M3  - 10.1038/41358
N1  - 10.1038/41358
UR  - http://dx.doi.org/10.1038/41358
ER  -

TY  - JOUR
AU  - Girard, P. M.
AU  - Kysela, B.
AU  - Harer, C. J.
AU  - Doherty, A. J.
AU  - Jeggo, P. A.
TI  - Analysis of DNA ligase IV mutations found in LIG4 syndrome patients: the impact of two linked polymorphisms
JA  - Hum. Mol. Genet.
PY  - 2004///
VL  - 13
SP  - 2369
EP  - 2376
M3  - 10.1093/hmg/ddh274
N1  - 10.1093/hmg/ddh274
UR  - http://dx.doi.org/10.1093/hmg/ddh274
ER  -

TY  - JOUR
AU  - Okada, S.
TI  - In vivo and in vitro stem cell function of c-kit- and Sca-1-positive murine hematopoietic cells
JA  - Blood
PY  - 1992///
VL  - 80
SP  - 3044
EP  - 3050
ER  -

TY  - JOUR
AU  - Morrison, S. J.
AU  - Wandycz, A. M.
AU  - Akashi, K.
AU  - Globerson, A.
AU  - Weissman, I. L.
TI  - The aging of hematopoietic stem cells
JA  - Nature Med.
PY  - 1996///
VL  - 2
SP  - 1011
EP  - 1016
M3  - 10.1038/nm0996-1011
N1  - 10.1038/nm0996-1011
UR  - http://dx.doi.org/10.1038/nm0996-1011
ER  -

TY  - JOUR
AU  - Rossi, D. J.
TI  - Cell intrinsic alterations underlie hematopoietic stem cell aging
JA  - Proc. Natl Acad. Sci. USA
PY  - 2005///
VL  - 102
SP  - 9194
EP  - 9199
M3  - 10.1073/pnas.0503280102
N1  - 10.1073/pnas.0503280102
UR  - http://dx.doi.org/10.1073/pnas.0503280102
ER  -

TY  - JOUR
AU  - Bhattacharya, D.
AU  - Rossi, D. J.
AU  - Bryder, D.
AU  - Weissman, I. L.
TI  - Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning
JA  - J. Exp. Med.
PY  - 2006///
VL  - 203
SP  - 73
EP  - 85
M3  - 10.1084/jem.20051714
N1  - 10.1084/jem.20051714
UR  - http://dx.doi.org/10.1084/jem.20051714
ER  -

TY  - JOUR
AU  - Hasty, P.
AU  - Vijg, J.
TI  - Accelerating aging by mouse reverse genetics: a rational approach to understanding longevity
JA  - Aging Cell
PY  - 2004///
VL  - 3
SP  - 55
EP  - 65
M3  - 10.1111/j.1474-9728.2004.00082.x
N1  - 10.1111/j.1474-9728.2004.00082.x
UR  - http://dx.doi.org/10.1111/j.1474-9728.2004.00082.x
ER  -

TY  - JOUR
AU  - Cheng, T.
TI  - Hematopoietic stem cell quiescence maintained by p21cip1/waf1
JA  - Science
PY  - 2000///
VL  - 287
SP  - 1804
EP  - 1808
M3  - 10.1126/science.287.5459.1804
N1  - 10.1126/science.287.5459.1804
UR  - http://dx.doi.org/10.1126/science.287.5459.1804
ER  -

TY  - JOUR
AU  - Hock, H.
TI  - Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
JA  - Nature
PY  - 2004///
VL  - 431
SP  - 1002
EP  - 1007
M3  - 10.1038/nature02994
N1  - 10.1038/nature02994
UR  - http://dx.doi.org/10.1038/nature02994
ER  -

TY  - JOUR
AU  - Orelio, C.
AU  - Dzierzak, E.
TI  - Bcl-2 expression and apoptosis in the regulation of hematopoietic stem cells
JA  - Leuk. Lymphoma
PY  - 2007///
VL  - 48
SP  - 16
EP  - 24
ER  -

TY  - JOUR
AU  - Becker, K. A.
AU  - Stein, J. L.
AU  - Lian, J. B.
AU  - van Wijnen, A. J.
AU  - Stein, G. S.
TI  - Establishment of histone gene regulation and cell cycle checkpoint control in human embryonic stem cells
JA  - J. Cell. Physiol.
PY  - 2007///
VL  - 210
SP  - 517
EP  - 526
M3  - 10.1002/jcp.20903
N1  - 10.1002/jcp.20903
UR  - http://dx.doi.org/10.1002/jcp.20903
ER  -

TY  - JOUR
AU  - Marchetti, C.
TI  - Identification of a novel motif in DNA ligases exemplified by DNA ligase IV
JA  - DNA Repair (Amst.)
PY  - 2006///
VL  - 5
SP  - 788
EP  - 798
ER  -

TY  - JOUR
AU  - Cabuy, E.
AU  - Newton, C.
AU  - Roberts, T.
AU  - Newbold, R.
AU  - Slijepcevic, P.
TI  - Identification of subpopulations of cells with differing telomere lengths in mouse and human cell lines by flow FISH
JA  - Cytometry A
PY  - 2004///
VL  - 62
SP  - 150
EP  - 161
M3  - 10.1002/cyto.a.20096
N1  - 10.1002/cyto.a.20096
UR  - http://dx.doi.org/10.1002/cyto.a.20096
ER  -

TY  - JOUR
AU  - Rodrigues, N. P.
TI  - Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis
JA  - Blood
PY  - 2005///
VL  - 106
SP  - 477
EP  - 484
M3  - 10.1182/blood-2004-08-2989
N1  - 10.1182/blood-2004-08-2989
UR  - http://dx.doi.org/10.1182/blood-2004-08-2989
ER  -

TY  - JOUR
AU  - Vinuesa, C. G.
TI  - A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity
JA  - Nature
PY  - 2005///
VL  - 435
SP  - 452
EP  - 458
M3  - 10.1038/nature03555
N1  - 10.1038/nature03555
UR  - http://dx.doi.org/10.1038/nature03555
ER  -
