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Nature 447, 649-650 (7 June 2007) | doi:10.1038/447649a; Published online 6 June 2007
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Endowed Professorship
- Washington University School of Medicine in St. Louis
- St. Louis, MO 63110 United States
Chief Scientific Manager - Medicinal Chemistry
- Syngene International
- Bangalore, Karnataka 560099 India
Stem cells: Recycling the abnormal
Alan Colman1 & Justine Burley2
Abstract
Using human eggs in the quest to make donor-specific embryonic stem cells is controversial. A method developed in mice, if applicable to humans, could eliminate the need to obtain eggs for this purpose.
On page 679 of this issue, Egli et al.1 describe a promising method for generating embryonic stem-cell (ESC) lineages using the technique of somatic-cell nuclear transfer (SCNT). Conventional SCNT involves replacement of the nuclear genetic material of an unfertilized egg (oocyte), with that of a somatic (non-germ) cell.
- Alan Colman is at ES Cell International and the A*STAR Institute of Medical Biology, 11 Biopolis Way, 05–06 Helios, Singapore 138667.
Email: acolman@escellinternational.com - Justine Burley is in the Graduate School for Integrative Sciences and Engineering, National University of Singapore, CeLS 05–01, 28 Medical Drive, Singapore 117456.
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