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Nature 447, 645-646 (7 June 2007) | doi:10.1038/447645a; Published online 6 June 2007

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Genomics: Guilt by association

Anne M. Bowcock1

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In a tour-de-force demonstration of feasibility, a consortium of 50 research teams uses 500,000 genetic markers from each of 17,000 individuals to identify 24 genetic risk factors for 7 common human diseases.

Mr Woodhouse, the comical hypochondriac of Jane Austen's Emma, takes great comfort in blaming his various ailments on the rain, the cold and an unfortunate piece of wedding cake. He would, no doubt, have been greatly surprised to learn that even his most rudimentary ailments resulted, at least in part, from genetic factors.

  1. Anne M. Bowcock is in the Departments of Genetics, Pediatrics and Medicine, Division of Human Genetics, Washington University School of Medicine, 4559 Scott Avenue, Saint Louis, Missouri 63110, USA.
    Email: bowcock@genetics.wustl.edu

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