Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 447, 536-537 (31 May 2007) | doi:10.1038/447536a; Published online 30 May 2007
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
- More Challenges
- Powered by:
nature jobs
Molecular Biologists and Biochemists
- University of Minnesota
- Minnesota, USA
Faculty - Plant Cellular & Molecular Biology, Molecular Genetics & the Plant Molecular Biology / Biotechnology Program
- The Ohio State University
- Columbus, Ohio
Ageing: When less is more
Adam Antebi1
Abstract
Restricting dietary intake is one way to promote longevity. The identification of two genes that specifically mediate this effect in worms provides insight into the molecular mechanisms underlying ageing.
Dietary restriction — a reduction of food intake by 40–60% without malnutrition — has remarkable benefits for health and lifespan, extending the survival of species as diverse as yeast, worms, flies, rodents and perhaps even primates. Yet despite intensive study, the molecular basis of the effects of dietary restriction in animals has remained largely elusive.
- Adam Antebi is at the Huffington Center on Aging and the Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.
Email: aantebi@bcm.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Cancer When restriction is goodNature News and Views (09 Apr 2009)
Aging and cancer: killing two birds with one wormNature Genetics News and Views (01 Nov 2007)
See all 3 matches for News And ViewsRESEARCH
PHA-4/Foxa mediates diet-restriction-induced longevity of C. elegansNature Article (31 May 2007)
Signalling through RHEB-1 mediates intermittent fasting-induced longevity in C. elegansNature Letters to Editor (05 Feb 2009)
See all 8 matches for Research