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Nature 447, 487-492 (9 May 2007) | doi:10.1038/nature05804;
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Redox-mediated substrate recognition by Sdp1 defines a new group of tyrosine phosphatases
Reactive oxygen species trigger cellular responses by activation of stress-responsive mitogen-activated protein kinase (MAPK) signalling pathways. Reversal of MAPK activation requires the transcriptional induction of specialized cysteine-based phosphatases that mediate MAPK dephosphorylation.
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