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Nature 447, 391-393 (24 May 2007) | doi:10.1038/447391a; Published online 23 May 2007

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Molecular biology: RNA in control

Benjamin J. Blencowe1 & May Khanna1

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In bacteria, some messenger RNAs can sense the need for their protein product and accordingly regulate expression of their own genes. A similar type of RNA regulation has now been revealed in higher organisms.

The functional capacity of RNA, beyond its role in protein synthesis, frequently amazes, as examples of RNA-mediated gene regulation are continuously emerging. One type of such regulation found in bacteria involves RNA structures called riboswitches.

  1. Benjamin J. Blencowe and May Khanna are in the Banting and Best Department of Medical Research, the Department of Molecular and Medical Genetics and the Centre for Cellular and Biomolecular Research, Donnelly CCBR Building, University of Toronto, 160 College Street, Toronto, Ontario M5S 3E1, Canada.
    Email: b.blencowe@utoronto.ca

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