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News and Views
Nature 447, 386-387 (24 May 2007) | doi:10.1038/447386a; Published online 23 May 2007
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Circadian rhythms: Metabolic clockwork
Benedetto Grimaldi1 & Paolo Sassone-Corsi1
Abstract
The 'body clock' regulates the daily cycles of many physiological and metabolic processes, but just how is a mystery. New findings suggest that the cycling of energy metabolism is mediated by an activator of gene expression.
Intuitively, we all feel that the activities of our bodies follow cycles of repeated oscillations. Unmistakable examples are the sleep–wake cycle, the feeding rhythm and variations in body temperature and hormonal levels.
- Benedetto Grimaldi and Paolo Sassone-Corsi are in the Department of Pharmacology, School of Medicine, University of California, Irvine, California 92697, USA.
Email: psc@uci.edu
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