FIGURE 3. Latently infected mice are resistant to Y. pestis but not WNV.
From the following article:
Herpesvirus latency confers symbiotic protection from bacterial infection
Erik S. Barton, Douglas W. White, Jason S. Cathelyn, Kelly A. Brett-McClellan, Michael Engle, Michael S. Diamond, Virginia L. Miller & Herbert W. Virgin, IV
Nature 447, 326-329(17 May 2007)
doi:10.1038/nature05762
a–d, Bacterial titres in mock (black symbols) or latently infected (
HV68, red symbols) mice challenged intranasally (a, 24 hours past infection (h.p.i.), lung, b, 48 h.p.i.) or subcutaneously (c, 36 h.p.i., spleen, d, 60 h.p.i.) with Y. pestis. P values, calculated using the Mann–Whitney rank sum test, compare latently infected and mock-infected mice (two independent experiments). X indicates death before harvest. Horizontal bars indicate the arithmetic mean of log-transformed data. The dashed line represents the limit of detection. Where not indicated, P > 0.08. e, Survival of mock or latently infected mice challenged by footpad inoculation with WNV. The P value was calculated using logrank analysis with ten mice per group.
