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Nature 447, 153-155 (10 May 2007) | doi:10.1038/447153a; Published online 9 May 2007

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Developmental biology: A chordate with a difference

Linda Z. Holland1

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Molecular studies of tunicate development show that genetic programmes for early embryonic patterning can change radically during evolution, without completely disrupting the basic chordate body plan.

The tunicates are our closest invertebrate relatives, being members, along with us and all other vertebrates, of the phylum Chordata. There are three groups of tunicates, and investigations of a member of one of them, the appendicularian Oikopleura dioica, has revealed an instructive anomaly among chordates.

  1. Linda Z. Holland is at the Scripps Institution of Oceanography, University of California, San Diego, La Jolla, California 92093-0202, USA.
    Email: lzholland@ucsd.edu

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