Provider: Nature Publishing Group
Content: application/x-research-info-systems
TY  - JOUR
AU  - Mendell, J. T.
AU  - Dietz, H. C.
TI  - When the message goes awry: disease-producing mutations that influence mRNA content and performance
JA  - Cell
PY  - 2001///
VL  - 107
SP  - 411
EP  - 414
M3  - 10.1016/S0092-8674(01)00583-9
N1  - 10.1016/S0092-8674(01)00583-9
UR  - http://dx.doi.org/10.1016/S0092-8674(01)00583-9
ER  -

TY  - JOUR
AU  - Kerem, E.
TI  - Pharmacologic therapy for stop mutations: how much CFTR activity is enough?
JA  - Curr. Opin. Pulm. Med.
PY  - 2004///
VL  - 10
SP  - 547
EP  - 552
M3  - 10.1097/01.mcp.0000141247.22078.46
N1  - 10.1097/01.mcp.0000141247.22078.46
UR  - http://dx.doi.org/10.1097/01.mcp.0000141247.22078.46
ER  -

TY  - JOUR
AU  - Ramalho, A. S.
TI  - Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis
JA  - Am. J. Respir. Cell Mol. Biol.
PY  - 2002///
VL  - 27
SP  - 619
EP  - 627
ER  -

TY  - JOUR
AU  - Maquat, L. E.
TI  - Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics
JA  - Nature Rev. Mol. Cell Biol.
PY  - 2004///
VL  - 5
SP  - 89
EP  - 99
M3  - 10.1038/nrm1310
N1  - 10.1038/nrm1310
UR  - http://dx.doi.org/10.1038/nrm1310
ER  -

TY  - JOUR
AU  - Amrani, N.
TI  - Sachs M. S. & Jacobson, A. Early nonsense: mRNA decay solves a translational problem
JA  - Nature Rev. Mol. Cell Biol.
PY  - 2006///
VL  - 7
SP  - 415
EP  - 425
M3  - 10.1038/nrm1942
N1  - 10.1038/nrm1942
UR  - http://dx.doi.org/10.1038/nrm1942
ER  -

TY  - GEN
AU  - Welch, E. M.
AU  - Wang, W.
AU  - Peltz, S. W.
TI  - Translational Control of Gene Expression
PY  - 2000///
SP  - 467
EP  - 486
ER  -

TY  - JOUR
AU  - Maderazo, A. B.
AU  - He, F.
AU  - Mangus, D. A.
AU  - Jacobson, A.
TI  - Upf1p control of nonsense mRNA translation is regulated by Nmd2p and Upf3p
JA  - Mol. Cell. Biol.
PY  - 2000///
VL  - 20
SP  - 4591
EP  - 4603
M3  - 10.1128/MCB.20.13.4591-4603.2000
N1  - 10.1128/MCB.20.13.4591-4603.2000
UR  - http://dx.doi.org/10.1128/MCB.20.13.4591-4603.2000
ER  -

TY  - JOUR
AU  - Weng, Y.
AU  - Czaplinski, K.
AU  - Peltz, S. W.
TI  - Genetic and biochemical characterization of mutations in the ATPase and helicase regions of the Upf1 protein
JA  - Mol. Cell. Biol.
PY  - 1996///
VL  - 16
SP  - 5477
EP  - 5490
ER  -

TY  - JOUR
AU  - Weng, Y.
AU  - Czaplinski, K.
AU  - Peltz, S. W.
TI  - Identification and characterization of mutations in the UPF1 gene that affect nonsense suppression and the formation of the Upf protein complex but not mRNA turnover
JA  - Mol. Cell. Biol.
PY  - 1996///
VL  - 16
SP  - 5491
EP  - 5506
ER  -

TY  - JOUR
AU  - Wang, W.
AU  - Czaplinski, K.
AU  - Rao, Y.
AU  - Peltz, S. W.
TI  - The role of Upf proteins in modulating the translation read-through of nonsense-containing transcripts
JA  - EMBO J.
PY  - 2001///
VL  - 20
SP  - 880
EP  - 890
M3  - 10.1093/emboj/20.4.880
N1  - 10.1093/emboj/20.4.880
UR  - http://dx.doi.org/10.1093/emboj/20.4.880
ER  -

TY  - JOUR
AU  - Manuvakhova, M.
AU  - Keeling, K.
AU  - Bedwell, D. M.
TI  - Aminoglycoside antibiotics mediate context-dependent suppression of termination codons in a mammalian translation system
JA  - RNA
PY  - 2000///
VL  - 6
SP  - 1044
EP  - 1055
M3  - 10.1017/S1355838200000716
N1  - 10.1017/S1355838200000716
UR  - http://dx.doi.org/10.1017/S1355838200000716
ER  -

TY  - JOUR
AU  - Politano, L.
TI  - Gentamicin administration in Duchenne patients with premature stop codon. Preliminary results
JA  - Acta Myol.
PY  - 2003///
VL  - 22
SP  - 15
EP  - 21
ER  -

TY  - JOUR
AU  - Clancy, J. P.
TI  - Evidence that systemic gentamicin suppresses premature stop mutations in patients with cystic fibrosis
JA  - Am. J. Respir. Crit. Care Med.
PY  - 2001///
VL  - 163
SP  - 1683
EP  - 1692
ER  -

TY  - JOUR
AU  - Wilschanski, M.
TI  - Gentamicin-induced correction of CFTR function in patients with cystic fibrosis and CFTR stop mutations
JA  - N. Engl. J. Med.
PY  - 2003///
VL  - 349
SP  - 1433
EP  - 1441
M3  - 10.1056/NEJMoa022170
N1  - 10.1056/NEJMoa022170
UR  - http://dx.doi.org/10.1056/NEJMoa022170
ER  -

TY  - JOUR
AU  - Wagner, K. R.
TI  - Gentamicin treatment of Duchenne and Becker muscular dystrophy due to nonsense mutations
JA  - Ann. Neurol.
PY  - 2001///
VL  - 49
SP  - 706
EP  - 711
M3  - 10.1002/ana.1023.abs
N1  - 10.1002/ana.1023.abs
UR  - http://dx.doi.org/10.1002/ana.1023.abs
ER  -

TY  - JOUR
AU  - Barton-Davis, E. R.
AU  - Cordier, L.
AU  - Shoturma, D. I.
AU  - Leland, S. E.
AU  - Sweeney, H. L.
TI  - Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice
JA  - J. Clin. Invest.
PY  - 1999///
VL  - 104
SP  - 375
EP  - 381
ER  -

TY  - JOUR
AU  - Bonetti, B.
AU  - Fu, L.
AU  - Moon, J.
AU  - Bedwell, D. M.
TI  - The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae
JA  - J. Mol. Biol.
PY  - 1995///
VL  - 251
SP  - 334
EP  - 345
M3  - 10.1006/jmbi.1995.0438
N1  - 10.1006/jmbi.1995.0438
UR  - http://dx.doi.org/10.1006/jmbi.1995.0438
ER  -

TY  - JOUR
AU  - McCaughan, K. K.
AU  - Brown, C. M.
AU  - Dalphin, M. E.
AU  - Berry, M. J.
AU  - Tate, W. P.
TI  - Translational termination efficiency in mammals is influenced by the base following the stop codon
JA  - Proc. Natl Acad. Sci. USA
PY  - 1995///
VL  - 92
SP  - 5431
EP  - 5435
M3  - 10.1073/pnas.92.12.5431
N1  - 10.1073/pnas.92.12.5431
UR  - http://dx.doi.org/10.1073/pnas.92.12.5431
ER  -

TY  - JOUR
AU  - Howard, M. T.
TI  - Sequence specificity of aminoglycoside-induced stop condon readthrough: potential implications for treatment of Duchenne muscular dystrophy
JA  - Ann. Neurol.
PY  - 2000///
VL  - 48
SP  - 164
EP  - 169
M3  - 10.1002/1531-8249(200008)48:2<164::AID-ANA5>3.3.CO;2-2
N1  - 10.1002/1531-8249(200008)48:2<164::AID-ANA5>3.3.CO;2-2
UR  - http://dx.doi.org/10.1002/1531-8249(200008)48:2<164::AID-ANA5>3.3.CO;2-2
ER  -

TY  - JOUR
AU  - Petrof, B. J.
AU  - Shrager, J. B.
AU  - Stedman, H. H.
AU  - Kelly, A. M.
AU  - Sweeney, H. L.
TI  - Dystrophin protects the sarcolemma from stresses developed during muscle contraction
JA  - Proc. Natl Acad. Sci. USA
PY  - 1993///
VL  - 90
SP  - 3710
EP  - 3714
M3  - 10.1073/pnas.90.8.3710
N1  - 10.1073/pnas.90.8.3710
UR  - http://dx.doi.org/10.1073/pnas.90.8.3710
ER  -

TY  - JOUR
AU  - Jacobson, A.
AU  - Peltz, S. W.
TI  - Interrelationships of the pathways of mRNA decay and translation in eukaryotic cells
JA  - Annu. Rev. Biochem.
PY  - 1996///
VL  - 65
SP  - 693
EP  - 739
M3  - 10.1146/ANNUREV.BIOCHEM.65.1.693
N1  - 10.1146/ANNUREV.BIOCHEM.65.1.693
UR  - http://dx.doi.org/10.1146/ANNUREV.BIOCHEM.65.1.693
ER  -

TY  - JOUR
AU  - Mendell, J. T.
AU  - Sharifi, N. A.
AU  - Meyers, J. L.
AU  - Martinez-Murillo, F.
AU  - Dietz, H. C.
TI  - Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise
JA  - Nature Genet.
PY  - 2004///
VL  - 36
SP  - 1073
EP  - 1078
M3  - 10.1038/ng1429
N1  - 10.1038/ng1429
UR  - http://dx.doi.org/10.1038/ng1429
ER  -

TY  - JOUR
AU  - Amrani, N.
TI  - A faux 3[prime]-UTR promotes aberrant termination and triggers nonsense-mediated mRNA decay
JA  - Nature
PY  - 2004///
VL  - 432
SP  - 112
EP  - 118
M3  - 10.1038/nature03060
N1  - 10.1038/nature03060
UR  - http://dx.doi.org/10.1038/nature03060
ER  -

TY  - JOUR
AU  - Hirawat, S.
TI  - Safety, tolerability, and pharmacokinetics of PTC124, a nonaminoglycoside nonsense mutation suppressor, following single- and multiple-dose administration to healthy male and female adult volunteers
JA  - J. Clin. Pharm.
PY  - 2007///
VL  - 47
SP  - 430
EP  - 444
M3  - 10.1177/0091270006297140
N1  - 10.1177/0091270006297140
UR  - http://dx.doi.org/10.1177/0091270006297140
ER  -

TY  - JOUR
AU  - He, F.
TI  - Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5[prime] to 3[prime] mRNA decay pathways in yeast
JA  - Mol. Cell
PY  - 2003///
VL  - 12
SP  - 1439
EP  - 1452
M3  - 10.1016/S1097-2765(03)00446-5
N1  - 10.1016/S1097-2765(03)00446-5
UR  - http://dx.doi.org/10.1016/S1097-2765(03)00446-5
ER  -

TY  - JOUR
AU  - Pruitt, K. D.
AU  - Maglott, D. R.
TI  - RefSeq and LocusLink: NCBI gene-centered resources
JA  - Nucleic Acids Res.
PY  - 2001///
VL  - 29
SP  - 137
EP  - 140
M3  - 10.1093/nar/29.1.137
N1  - 10.1093/nar/29.1.137
UR  - http://dx.doi.org/10.1093/nar/29.1.137
ER  -

TY  - JOUR
AU  - Frischmeyer, P. A.
TI  - An mRNA surveillance mechanism that eliminates transcripts lacking termination codons
JA  - Science
PY  - 2002///
VL  - 295
SP  - 2258
EP  - 2261
M3  - 10.1126/science.1067338
N1  - 10.1126/science.1067338
UR  - http://dx.doi.org/10.1126/science.1067338
ER  -

TY  - JOUR
AU  - van Hoof, H. A.
AU  - Frischmeyer, P. A.
AU  - Dietz, H. C.
AU  - Parker, R.
TI  - Exosome-mediated recognition and degradation of mRNAs lacking a termination codon
JA  - Science
PY  - 2002///
VL  - 295
SP  - 2262
EP  - 2264
M3  - 10.1126/science.1067272
N1  - 10.1126/science.1067272
UR  - http://dx.doi.org/10.1126/science.1067272
ER  -

TY  - GEN
AU  - Sambrook, J.
AU  - Fritsch, E.
AU  - Maniatis, T.
TI  - Molecular cloning: a laboratory manual
PY  - 1989///
ER  -

TY  - JOUR
AU  - Grentzmann, G.
AU  - Ingram, J. A.
AU  - Kelly, P. J.
AU  - Gesteland, R. F.
AU  - Atkins, J. F.
TI  - A dual-luciferase reporter system for studying recoding signals
JA  - RNA
PY  - 1998///
VL  - 4
SP  - 479
EP  - 486
M3  - 10.1017/S1355838298971576
N1  - 10.1017/S1355838298971576
UR  - http://dx.doi.org/10.1017/S1355838298971576
ER  -

TY  - JOUR
AU  - Van Der Velden, V.
AU  - Kaminski, A.
AU  - Jackson, R. J.
AU  - Belsham, G. J.
TI  - Defective point mutants of the encephalomyocarditis virus internal ribosome entry site can be complemented in trans
JA  - Virology
PY  - 1995///
VL  - 214
SP  - 82
EP  - 90
M3  - 10.1006/viro.1995.9952
N1  - 10.1006/viro.1995.9952
UR  - http://dx.doi.org/10.1006/viro.1995.9952
ER  -

TY  - JOUR
AU  - Jang, S. K.
TI  - A segment of the 5[prime]-nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation
JA  - J. Virol.
PY  - 1988///
VL  - 62
SP  - 2636
EP  - 2643
ER  -

TY  - GEN
AU  - Neville, C.
AU  - Rosenthal, N.
AU  - McGrew, M.
AU  - Bogdanova, N.
AU  - Hauschka, S.
TI  - Methods in Cell Biology 52
PY  - 1998///
SP  - 85
EP  - 116
ER  -

TY  - JOUR
AU  - Sweeney, H. L.
AU  - Feng, H.
TI  - Structure-function analysis of cytoskeletal/contractile proteins in avian myotubes
JA  - Methods Cell Biol.
PY  - 1997///
VL  - 52
SP  - 275
EP  - 282
ER  -

TY  - JOUR
AU  - O'Farrell, P. H.
TI  - High resolution two-dimensional electrophoresis of proteins
JA  - J. Biol. Chem.
PY  - 1975///
VL  - 250
SP  - 4007
EP  - 4021
ER  -