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Nature 447, 92-96 (22 April 2007) | doi:10.1038/nature05746;
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Chitin induces accumulation in tissue of innate immune cells associated with allergy
Allergic and parasitic worm immunity is characterized by infiltration of tissues with interleukin (IL)-4- and IL-13-expressing cells, including T-helper-2 cells, eosinophils and basophils. Tissue macrophages assume a distinct phenotype, designated alternatively activated macrophages.
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