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Nature 446, 999 (26 April 2007) | doi:10.1038/446999a; Published online 25 April 2007

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Glycochemistry & Glycobiology

Joshua Finkelstein1

Carbohydrates have long been underappreciated by the scientific community, and many scientists approach the complex structures and elaborate nomenclature of carbohydrates with trepidation. Like amino acids and nucleic acids, sugars are abundant in nature: many natural products contain oligosaccharides that are vital for their biological activity, and carbohydrates have key roles in a broad range of biological processes, including signal transduction and immune responses.

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