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Essay
Nature 446, 983 (26 April 2007) | doi:10.1038/446983a; Published online 25 April 2007
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Head of Production Biopharmaceuticals
- Rhein Minapharm Biogenetics
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Senior Statistical Genetics in High-throughput Sequencing Analysis
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James A. Lake1
- James A. Lake is distinguished professor in the Departments of MCD Biology and Human Genetics, and in the Molecular Biology Institute, University of California, Los Angeles, 242 Boyer Hall, Los Angeles, California 90095, USA.
Abstract
The bizarre absence of certain gene classes in eukaryotes is key to understanding their evolution and complex links with prokaryotes.
Eukaryotic evolution is something of a Gordian knot. Using single genes to unravel it won't work, as the genomes of eukaryotes (animals, plants, fungi and protists) are derived from those of several prokaryotes (eubacteria and archaebacteria).
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