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Nature 446, 868-869 (19 April 2007) | doi:10.1038/446868a; Published online 18 April 2007

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Cell biology: The checkpoint brake relieved

Jan-Michael Peters1

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When a cell divides, each daughter cell inherits a complete set of chromosomes. A sophisticated inhibitory mechanism delays chromosome segregation and cell division until everything is in its place.

It is equally important for a cell to do things at the right times as it is for an organism. This is particularly true during the final phase of cell division — mitosis — when chromosomes segregate.

  1. Jan-Michael Peters is at the Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.
    Email: peters@imp.univie.ac.at

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