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Nature 446, 745-747 (12 April 2007) | doi:10.1038/446745a; Published online 11 April 2007
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Cell biology: Autophagy and cancer
Beth Levine1
Abstract
Autophagy is the degradation of redundant or faulty cell components. It occurs as part of a cell's everyday activities and as a response to stressful stimuli, such as starvation. Connections with cellular life-and-death decisions and with cancer are now emerging.
How is autophagy induced?Autophagy occurs when cells need to 'self-cannibalize' or degrade their constituents.
- Beth Levine is in the Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9113, USA.
Email: beth.levine@utsouthwestern.edu
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