Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 446, 741-743 (12 April 2007) | doi:10.1038/446741a; Published online 11 April 2007
Open Innovation Challenges
-
Optimizing Sub-cellular Localization Tags
The Seeker is looking for methods to optimize sub-cellular localization tags for protein expression....
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
- More Challenges
- Powered by:
nature jobs
Chocolate Food Technologists
- Nestlé
- Broc, Switzerland
Fellowships
- Brighams and Women's Hospital
- Boston, MA
Cell biology: Fraternal twins
Franck Duong1
Abstract
A popular route for protein transport into and across cell membranes is through the Sec channel. This channel seems to function by forming a dimer of two identical units, where each has a distinct role.
The transmembrane Sec channel, or Sec translocon, is a major protein-transport route across the endoplasmic reticulum of higher organisms and the cell membrane of bacteria. This essential machinery ensures the correct distribution of cellular proteins, and catalyses the translocation, and membrane integration, of hundreds of different proteins that carry a specific targeting signal called the signal sequence.
- Franck Duong is in the Department of Biochemistry and Molecular Biology, Life Sciences Institute, Faculty of Medicine, University of British Columbia, Vancouver, British Columbia V6T 1Z3, Canada.
Email: fduong@interchange.ubc.ca
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Cell biology Two pores better than one?Nature News and Views (17 Nov 2005)
Structural biology Clamour for a kissNature News and Views (16 Oct 2008)
See all 4 matches for News And ViewsRESEARCH
Investigating the SecY plug movement at the SecYEG translocation channelThe EMBO Journal Article (05 Oct 2005)
X-ray structure of a protein-conducting channelNature Article (01 Jan 2004)
See all 34 matches for Research