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From the following article:

Epithelial NEMO links innate immunity to chronic intestinal inflammation

Arianna Nenci, Christoph Becker, Andy Wullaert, Ralph Gareus, Geert van Loo, Silvio Danese, Marion Huth, Alexei Nikolaev, Clemens Neufert, Blair Madison, Deborah Gumucio, Markus F. Neurath & Manolis Pasparakis

Nature 446, 557-561(29 March 2007)

doi:10.1038/nature05698

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Figure 1

Intestinal epithelium-specific NEMO ablation causes severe spontaneous colitis.

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Figure 2

Inflammation in the colon of NEMOIEC-KO mice.

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Figure 3

Compromised epithelial integrity and bacterial translocation in the colon of NEMOIEC-KO mice.

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Figure 4

NF-kappaB inhibition in intestinal epithelial cells causes inflammatory colitis that depends on TNFRI and MyD88 signalling. a,

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Figure 5

NEMO-mediated NF-kappaB activation in intestinal epithelial cells is essential for the maintenance of epithelial barrier integrity and immune homeostasis in the colon.

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