Provider: Nature Publishing Group
Content: application/x-research-info-systems
TY  - JOUR
AU  - Futreal, P. A.
TI  - A census of human cancer genes
JA  - Nature Rev. Cancer
PY  - 2004///
VL  - 4
SP  - 177
EP  - 183
M3  - 10.1038/nrc1299
N1  - 10.1038/nrc1299
UR  - http://dx.doi.org/10.1038/nrc1299
ER  -

TY  - JOUR
AU  - Futreal, P. A.
TI  - Cancer and genomics
JA  - Nature
PY  - 2001///
VL  - 409
SP  - 850
EP  - 852
M3  - 10.1038/35057046
N1  - 10.1038/35057046
UR  - http://dx.doi.org/10.1038/35057046
ER  -

TY  - JOUR
AU  - Sawyers, C.
TI  - Targeted cancer therapy
JA  - Nature
PY  - 2004///
VL  - 432
SP  - 294
EP  - 297
M3  - 10.1038/nature03095
N1  - 10.1038/nature03095
UR  - http://dx.doi.org/10.1038/nature03095
ER  -

TY  - JOUR
AU  - Manning, G.
AU  - Whyte, D. B.
AU  - Martinez, R.
AU  - Hunter, T.
AU  - Sudarsanam, S.
TI  - The protein kinase complement of the human genome
JA  - Science
PY  - 2002///
VL  - 298
SP  - 1912
EP  - 1934
M3  - 10.1126/science.1075762
N1  - 10.1126/science.1075762
UR  - http://dx.doi.org/10.1126/science.1075762
ER  -

TY  - JOUR
AU  - Stephens, P.
TI  - A screen of the complete protein kinase gene family identifies diverse patterns of somatic mutations in human breast cancer
JA  - Nature Genet.
PY  - 2005///
VL  - 37
SP  - 590
EP  - 592
M3  - 10.1038/ng1571
N1  - 10.1038/ng1571
UR  - http://dx.doi.org/10.1038/ng1571
ER  -

TY  - JOUR
AU  - Davies, H.
TI  - Somatic mutations of the protein kinase gene family in human lung cancer
JA  - Cancer Res.
PY  - 2005///
VL  - 65
SP  - 7591
EP  - 7595
ER  -

TY  - JOUR
AU  - Hunter, C.
TI  - A hypermutation phenotype and somatic MSH6 mutations in recurrent human malignant gliomas after alkylator chemotherapy
JA  - Cancer Res.
PY  - 2006///
VL  - 66
SP  - 3987
EP  - 3991
M3  - 10.1158/0008-5472.CAN-06-0127
N1  - 10.1158/0008-5472.CAN-06-0127
UR  - http://dx.doi.org/10.1158/0008-5472.CAN-06-0127
ER  -

TY  - JOUR
AU  - Bignell, G.
TI  - Sequence analysis of the protein kinase gene family in human testicular germ-cell tumours of adolescents and adults
JA  - Genes Chromosom. Cancer
PY  - 2006///
VL  - 45
SP  - 42
EP  - 46
M3  - 10.1002/gcc.20265
N1  - 10.1002/gcc.20265
UR  - http://dx.doi.org/10.1002/gcc.20265
ER  -

TY  - JOUR
AU  - Bardelli, A.
TI  - Mutational analysis of the tyrosine kinome in colorectal cancers
JA  - Science
PY  - 2003///
VL  - 300
SP  - 949
M3  - 10.1126/science.1082596
N1  - 10.1126/science.1082596
UR  - http://dx.doi.org/10.1126/science.1082596
ER  -

TY  - JOUR
AU  - Wang, T.-L.
TI  - Prevalence of somatic alterations in the colorectal cancer cell genome
JA  - Proc. Natl Acad. Sci. USA
PY  - 2002///
VL  - 99
SP  - 3076
EP  - 3080
M3  - 10.1073/PNAS.261714699
N1  - 10.1073/PNAS.261714699
UR  - http://dx.doi.org/10.1073/PNAS.261714699
ER  -

TY  - JOUR
AU  - Lonardi, S.
AU  - Tosoni, A.
AU  - Brandes, A. A.
TI  - Adjuvant chemotherapy in the treatment of high grade gliomas
JA  - Cancer Treat. Rev.
PY  - 2005///
VL  - 31
SP  - 79
EP  - 89
M3  - 10.1016/j.ctrv.2004.12.005
N1  - 10.1016/j.ctrv.2004.12.005
UR  - http://dx.doi.org/10.1016/j.ctrv.2004.12.005
ER  -

TY  - JOUR
AU  - Karran, P.
AU  - Offman, J.
AU  - Bignami, M.
TI  - Human mismatch repair, drug-induced DNA damage, and secondary cancer
JA  - Biochimie
PY  - 2003///
VL  - 85
SP  - 1149
EP  - 1160
M3  - 10.1016/j.biochi.2003.10.007
N1  - 10.1016/j.biochi.2003.10.007
UR  - http://dx.doi.org/10.1016/j.biochi.2003.10.007
ER  -

TY  - JOUR
AU  - Greenman, C.
AU  - Wooster, R.
AU  - Futreal, P. A.
AU  - Stratton, M. R.
AU  - Easton, D. F.
TI  - Statistical analysis of pathogenicity of somatic mutations in cancer
JA  - Genetics
PY  - 2006///
VL  - 173
SP  - 2187
EP  - 2198
M3  - 10.1534/genetics.105.044677
N1  - 10.1534/genetics.105.044677
UR  - http://dx.doi.org/10.1534/genetics.105.044677
ER  -

TY  - JOUR
AU  - Yang, Z.
AU  - Ro, S.
AU  - Rannala, B.
TI  - Likelihood models of somatic mutation and codon substitution in cancer genes
JA  - Genetics
PY  - 2003///
VL  - 165
SP  - 695
EP  - 705
ER  -

TY  - JOUR
AU  - Goldman, N.
AU  - Yang, Z.
TI  - A codon-based model of nucleotide substitution for protein-coding DNA sequences
JA  - Mol. Biol. Evol.
PY  - 1994///
VL  - 11
SP  - 725
EP  - 736
ER  -

TY  - JOUR
AU  - Sanchez-Cespedes, M.
TI  - Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung
JA  - Cancer Res.
PY  - 2002///
VL  - 62
SP  - 3659
EP  - 3662
ER  -

TY  - JOUR
AU  - Davies, H.
TI  - Mutations of the BRAF gene in human cancer
JA  - Nature
PY  - 2002///
VL  - 417
SP  - 949
EP  - 954
M3  - 10.1038/nature00766
N1  - 10.1038/nature00766
UR  - http://dx.doi.org/10.1038/nature00766
ER  -

TY  - JOUR
AU  - Granzier, H. L.
AU  - Labeit, S.
TI  - Titin and its associated proteins: the third myofilament system of the sarcomere
JA  - Adv. Protein Chem.
PY  - 2005///
VL  - 71
SP  - 89
EP  - 119
ER  -

TY  - JOUR
AU  - Machado, C.
AU  - Andrew, D. J.
TI  - D-Titin: a giant protein with dual roles in chromosomes and muscles
JA  - J. Cell Biol.
PY  - 2000///
VL  - 151
SP  - 639
EP  - 652
M3  - 10.1083/jcb.151.3.639
N1  - 10.1083/jcb.151.3.639
UR  - http://dx.doi.org/10.1083/jcb.151.3.639
ER  -

TY  - JOUR
AU  - Machado, C.
AU  - Sunkel, C. E.
AU  - Andrew, D. J.
TI  - Human autoantibodies reveal Titin as a chromosomal protein
JA  - J. Cell Biol.
PY  - 1998///
VL  - 141
SP  - 321
EP  - 333
M3  - 10.1083/jcb.141.2.321
N1  - 10.1083/jcb.141.2.321
UR  - http://dx.doi.org/10.1083/jcb.141.2.321
ER  -

TY  - JOUR
AU  - Zastrow, M. S.
AU  - Flaherty, D. B.
AU  - Benian, G. M.
AU  - Wilson, K. L.
TI  - Nuclear Titin interacts with A- and B-type lamins in vitro and in vivo
JA  - J. Cell Sci.
PY  - 2006///
VL  - 119
SP  - 239
EP  - 249
M3  - 10.1242/jcs.02728
N1  - 10.1242/jcs.02728
UR  - http://dx.doi.org/10.1242/jcs.02728
ER  -

TY  - JOUR
AU  - Shiloh, Y.
TI  - ATM and related protein kinases: safeguarding genome integrity
JA  - Nature Rev. Cancer
PY  - 2003///
VL  - 3
SP  - 155
EP  - 168
M3  - 10.1038/nrc1011
N1  - 10.1038/nrc1011
UR  - http://dx.doi.org/10.1038/nrc1011
ER  -

TY  - JOUR
AU  - Renwick, A.
TI  - ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles
JA  - Nature Genet.
PY  - 2006///
VL  - 38
SP  - 873
EP  - 875
M3  - 10.1038/ng1837
N1  - 10.1038/ng1837
UR  - http://dx.doi.org/10.1038/ng1837
ER  -

TY  - JOUR
AU  - Markowitz, S.
TI  - Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability
JA  - Science
PY  - 1995///
VL  - 268
SP  - 1336
EP  - 1338
M3  - 10.1126/science.7761852
N1  - 10.1126/science.7761852
UR  - http://dx.doi.org/10.1126/science.7761852
ER  -

TY  - JOUR
AU  - Howe, J. R.
TI  - Germline mutations of the gene encoding bone morphogenetic protein receptor 1A in juvenile polyposis
JA  - Nature Genet.
PY  - 2001///
VL  - 28
SP  - 184
EP  - 187
ER  -

TY  - JOUR
AU  - Wan, P. T. C.
TI  - Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF
JA  - Cell
PY  - 2004///
VL  - 116
SP  - 855
EP  - 867
M3  - 10.1016/S0092-8674(04)00215-6
N1  - 10.1016/S0092-8674(04)00215-6
UR  - http://dx.doi.org/10.1016/S0092-8674(04)00215-6
ER  -

TY  - JOUR
AU  - Irusta, P. M.
TI  - Definition of an inhibitory juxtamembrane WW-like domain in the platelet-derived growth factor beta receptor
JA  - J. Biol. Chem.
PY  - 2002///
VL  - 277
SP  - 38627
EP  - 38634
M3  - 10.1074/jbc.M204890200
N1  - 10.1074/jbc.M204890200
UR  - http://dx.doi.org/10.1074/jbc.M204890200
ER  -

TY  - JOUR
AU  - Teng, D.
TI  - Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
JA  - Cancer Res.
PY  - 1997///
VL  - 57
SP  - 4177
EP  - 4182
ER  -

TY  - JOUR
AU  - Su, G.
TI  - Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene
JA  - Cancer Res.
PY  - 1998///
VL  - 58
SP  - 2339
EP  - 2342
ER  -

TY  - JOUR
AU  - Parsons, D. W.
TI  - Colorectal cancer Mutations in a signalling pathway
JA  - Nature
PY  - 2005///
VL  - 436
SP  - 792
M3  - 10.1038/436792a
N1  - 10.1038/436792a
UR  - http://dx.doi.org/10.1038/436792a
ER  -

TY  - JOUR
AU  - Bogoyevitch, M. A.
AU  - Boehm, I.
AU  - Oakley, A.
AU  - Ketterman, A. J.
AU  - Barr, R. K.
TI  - Targeting the JNK MAPK cascade for inhibition: basic science and therapeutic potential
JA  - Biochim. Biophys. Acta
PY  - 2004///
VL  - 1697
SP  - 89
EP  - 101
ER  -

TY  - JOUR
AU  - Kyriakis, J. M.
AU  - Avruch, J.
TI  - Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JA  - Physiol. Rev.
PY  - 2001///
VL  - 81
SP  - 807
EP  - 869
ER  -

TY  - JOUR
AU  - Joshi-Tope, G.
TI  - Reactome: a knowledgebase of biological pathways
JA  - Nucleic Acids Res.
PY  - 2005///
VL  - 33
SP  - D428
EP  - D432
ER  -

TY  - JOUR
AU  - Mi, H.
TI  - The PANTHER database of protein families, subfamilies, functions and pathways
JA  - Nucleic Acids Res.
PY  - 2005///
VL  - 33
SP  - D284
EP  - D288
M3  - 10.1093/nar/gki078
N1  - 10.1093/nar/gki078
UR  - http://dx.doi.org/10.1093/nar/gki078
ER  -

TY  - JOUR
AU  - Kushida, T.
AU  - Takagi, T.
AU  - Fukuda, K.
TI  - Event ontology: a pathway-centric ontology for biological processes
JA  - Pac. Symp. Biocomput.
PY  - 2006///
VL  - 11
SP  - 152
EP  - 163
ER  -

TY  - JOUR
AU  - Wilkie, A.
AU  - Patey, S.
AU  - Kan, S.
AU  - van den Ouweland, A.
AU  - Hamel, B.
TI  - FGFs, their receptors, and human limb malformations: clinical and molecular correlations
JA  - Am. J. Med. Genet.
PY  - 2002///
VL  - 112
SP  - 266
EP  - 278
M3  - 10.1002/ajmg.10775
N1  - 10.1002/ajmg.10775
UR  - http://dx.doi.org/10.1002/ajmg.10775
ER  -

TY  - JOUR
AU  - Cappellen, D.
TI  - Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas
JA  - Nature Genet.
PY  - 1999///
VL  - 23
SP  - 18
EP  - 20
ER  -

TY  - JOUR
AU  - Sjoblom, T.
TI  - The consensus coding sequences of human breast and colorectal cancers
JA  - Science
PY  - 2006///
VL  - 314
SP  - 268
EP  - 274
M3  - 10.1126/science.1133427
N1  - 10.1126/science.1133427
UR  - http://dx.doi.org/10.1126/science.1133427
ER  -

TY  - JOUR
AU  - Brose, M. S.
TI  - BRAF and RAS mutations in human lung cancer and melanoma
JA  - Cancer Res.
PY  - 2002///
VL  - 62
SP  - 6997
EP  - 7000
ER  -