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Nature 446, 12 (1 March 2007) | doi:10.1038/446012a; Published online 28 February 2007

Scientists rethink approach to HIV gels

Erika Check

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Tough decisions follow failure of clinical trial.

Scientists and activists struggling to combat the HIV epidemic were shattered by last month's failure of a candidate microbicide gel in large clinical trials. Microbicides aim to block HIV infection, but the candidate product — cellulose sulphate — seemed to increase women's susceptibility.

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