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Nature 445, 833 (22 February 2007) | doi:10.1038/445833a; Published online 21 February 2007

Introduction Skin Biology

Barbara Marte1, Joshua Finkelstein1 & Lesley Anson1

Not only is skin the largest organ of the body, it is also one of the most multifaceted. It senses our surroundings and forms a protective barrier against many different environmental insults, including ultraviolet radiation and pathogens.