Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 445, 722-723 (15 February 2007) | doi:10.1038/445722a; Published online 14 February 2007
Open Innovation Challenges
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
nature jobs
Canada Research Chair (Tier 1) Alfred Bader Chair in Organic Chemistry
- Queens University
- Kingston, ON, Canada
Food Chemist & Bioactive Specialist
- Nestle Research Center
- Lausanne Switzerland
Vascular Biology: Vessel guidance
Thomas Gridley1
Abstract
Embryos and tumours use the same signalling pathways to direct the formation of blood vessels. Discovery of a new role for the Notch pathway in that process presents a fresh option for cancer treatment.
Angiogenesis, the growth of new blood vessels from existing ones, is a highly active process in embryos. In adults, blood vessels in most organs are quiescent — except, notably, during the growth of solid tumours, when embryonic signalling pathways direct new blood vessels to grow around and into the tumour.
- Thomas Gridley is at The Jackson Laboratory,
Bar Harbor, Maine 04609, USA.
Email: tom.gridley@jax.org
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Promoting angiogenesis to a faultNature Biotechnology News and Views (01 Mar 2007)
Promoting angiogenesis to a faultNature Biotechnology News and Views (01 Mar 2007)
See all 4 matches for News And ViewsRESEARCH
Identification of IGFBP-6 as an effector of the tumor suppressor activity of SEMA3BOncogene Original Article
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formationNature Letters to Editor (31 Jul 2008)
See all 9 matches for Research
