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From the following article:

Restoration of p53 function leads to tumour regression in vivo

Andrea Ventura, David G. Kirsch, Margaret E. McLaughlin, David A. Tuveson, Jan Grimm, Laura Lintault, Jamie Newman, Elizabeth E. Reczek, Ralph Weissleder & Tyler Jacks

Nature 445, 661-665(8 February 2007)

doi:10.1038/nature05541

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Figure 1

Generation of the p53-LSL allele.

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Figure 2

p53 restoration leads to tumour regression in vivo.

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Figure 3

p53 restoration in lymphomas leads to apoptosis.

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Figure 4

p53 restoration in sarcomas leads to growth suppression with features of cellular senescence.

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