Figures and Tables

From the following article:

Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast

Philip Zegerman and John F. X. Diffley

Nature 445, 281-285(18 January 2007)

doi:10.1038/nature05432

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, or to obtain a text description, please contact npg@nature.com

Figure 1

Sld3 is an essential CDK substrate.

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Figure 2

CDK-phosphorylated Sld3 binds to Dpb11.

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Figure 3

Dpb11–Sld3 interaction is the essential function of Sld3 CDK phosphorylation sites and the N terminus of Dpb11.

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Figure 4

DNA replication in the absence of S-CDK activity.

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Figure 5

CDK bypass and Dbf4 overexpression allows replication in G1 cells.

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