Table of contents
Volume 445 Number 7124 pp125-223
(this content only available online) indicates content that is available online only
Editorials
A corporate response to AIDS p125
Private-sector employers who face up to the HIV epidemic in Africa must be encouraged, not harangued.
doi:10.1038/445125a
Off the rails p125
Aviation's role in climate change is causing a storm.
doi:10.1038/445125b
Competitive stumbling p126
Promised investment in the physical sciences is held up in a US budget jam.
doi:10.1038/445126a
News
Power shift stymies US science budget p130
Spending plans in limbo as Democrats take over Congress.
Geoff Brumfiel
doi:10.1038/445130a
Special report
Out of bounds p132
With the use of transgenic crops expanding around the globe, we need to decide what level of unapproved plants we are willing to accept in our diets. Zero is not an option, says Heidi Ledford.
doi:10.1038/445132a
Congress and Bush set to clash on stem cells again p134
House and Senate will challenge president's veto.
Meredith Wadman
doi:10.1038/445134a
Indian science is in decline, says prime minister p134
Manmohan Singh calls for India's scientists to raise their game in return for increased funding.
K. S. Jayaraman
doi:10.1038/445134b
Sidelines p136
doi:10.1038/445136a
Immigration policy forces researchers out of West Bank p136
Foreign nationals denied access to universities.
Jim Giles
doi:10.1038/445136b
Business
Reinventing an industry p138
Two years after a radical change that brought India's patent laws into line with international trading rules, the country's drug makers are taking a new direction. Apoorva Mandavilli reports.
doi:10.1038/445138a
In brief p139
doi:10.1038/445139a
Market watch p139
Colin Macilwain
doi:10.1038/445139b
News Features
AIDS: On the Brink p140
Containing a potential HIV explosion in the strife-torn Niger delta is a tough job — but circumstances are forcing the oil and gas industries to confront it. Colin Macilwain reports.
doi:10.1038/445140a
Quantum games: States of play p144
Life is full of events that are basically games, from paying for a meal to bidding in an auction. Can incorporating a quantum strategy into the rule book increase your chances of winning? Navroz Patel reports.
doi:10.1038/445144a
See also: Editor's summary
Correspondence
Hidden subsidies and risks pump up real price of oil p147
Dick Lugar
doi:10.1038/445147a
Poaching laws are useless without solid enforcement p147
Brian Gratwicke
doi:10.1038/445147b
Turks fighting back against anti-evolution forces p147
Mehmet Somel, Rahsan Nazli Ozturkler Somel & Aykut Kence
doi:10.1038/445147c
Readers see red over low-impact graphics p147
Chris Miall
doi:10.1038/445147d
Books and Arts
The supreme problem solver p149
An exploration of the life and science of physicist Hans Bethe.
David Wark reviews Hans Bethe and His Physics
doi:10.1038/445149a
A bird's-eye view p150
Andrew T. D. Bennett reviews Bird Coloration: Vol. 1, Mechanisms and Measurement; Vol. 2, Function and Evolution
doi:10.1038/445150a
A cultural state of mind p151
Lewis Wolpert reviews The Culture of Our Discontent: Beyond the Medical Model of Mental Illness by Meredith F. Small
doi:10.1038/445151a
In retrospect p152
Richard L. Gregory reviews The Memoirs of Sherlock Holmes: The Adventure of Silver Blaze by Arthur Conan Doyle
doi:10.1038/445152a
See also: Editor's summary
Essay
ConceptAdaptive Immunity: Care for the community p153
A memory-based immune system may have evolved in vertebrates because of the need to recognize and manage complex communities of beneficial microbes.
Margaret McFall-Ngai
doi:10.1038/445153a
See also: Editor's summary
News and Views
Palaeontology: Embryonic identity crisis p155
The oldest known animal fossils, identified as eggs and embryos, had been expected to reveal secrets from a period of great evolutionary change. Will the latest theory about the fossils' origins confound these hopes?
Philip C. J. Donoghue
doi:10.1038/nature05520
See also: Editor's summary
Particle physics: Hard-core revelations p156
Our description of how the atomic nucleus holds together has up to now been entirely empirical. Arduous calculations starting from the theory of the strong nuclear force provide a new way into matter's hard core.
Frank Wilczek
doi:10.1038/445156a
Developmental biology: Marked from the start p157
Helen Dell
doi:10.1038/445157a
See also: Editor's summary
50 & 100 Years Ago p158
doi:10.1038/445158a
Evolutionary biology: Genetics and bisexuality p158
A population-genetic model indicates that if there is a gene responsible for homosexual behaviour it can readily spread in populations. The model also predicts widespread bisexuality in humans.
Vincent Savolainen & Laurent Lehmann
doi:10.1038/445158b
Oceanography: A marine nitrogen cycle fix? p159
Some of our suppositions about the marine nitrogen cycle may be wrong. An innovative analysis of nutrients at the ocean's surface reveals a feedback mechanism that might hold the whole cycle in balance.
Douglas G. Capone & Angela N. Knapp
doi:10.1038/445159a
See also: Editor's summary
Bioinformatics: Industrializing neuroscience p160
The project for producing a genome-wide atlas of gene expression in the mouse brain shows how, with advancing technology, huge volumes of data can be collected and made accessible through the Internet.
Henry Markram
doi:10.1038/445160a
See also: Editor's summary
Materials Science: Displaced by radiation p161
The mineral zircon suffers more structural damage from the 
-decay of plutonium present in its crystal than was thought. That could have a knock-on effect on strategies for managing nuclear waste.
Rodney C. Ewing
doi:10.1038/445161a
See also: Editor's summary
Brief Communications Arising
Quantum Information: Source of triggered entangled photon pairs? pE4
Alexei Gilchrist, Kevin J. Resch & Andrew G. White
doi:10.1038/nature05546
First paragraph | Full Text | PDF (153K)
Quantum Information: Source of triggered entangled photon pairs? (Reply) pE5
R. Mark Stevenson, Robert J. Young, Paola Atkinson, Ken Cooper, David A. Ritchie & Andrew J. Shields
doi:10.1038/nature05547
First paragraph | Full Text | PDF (139K)
Articles
Spatial coupling of nitrogen inputs and losses in the ocean p163
Curtis Deutsch, Jorge L. Sarmiento, Daniel M. Sigman, Nicolas Gruber & John P. Dunne
doi:10.1038/nature05392
Abstract | Full Text | PDF (663K) | Supplementary information
See also: Editor's summary | News and Views by Capone & Knapp
Genome-wide atlas of gene expression in the adult mouse brain p168
Ed S. Lein, Michael J. Hawrylycz, Nancy Ao, Mikael Ayres, Amy Bensinger, Amy Bernard, Andrew F. Boe, Mark S. Boguski, Kevin S. Brockway, Emi J. Byrnes, Lin Chen, Li Chen, Tsuey-Ming Chen, Mei Chi Chin, Jimmy Chong, Brian E. Crook, Aneta Czaplinska, Chinh N. Dang, Suvro Datta, Nick R. Dee, Aimee L. Desaki, Tsega Desta, Ellen Diep, Tim A. Dolbeare, Matthew J. Donelan, Hong-Wei Dong, Jennifer G. Dougherty, Ben J. Duncan, Amanda J. Ebbert, Gregor Eichele, Lili K. Estin, Casey Faber, Benjamin A. Facer, Rick Fields, Shanna R. Fischer, Tim P. Fliss, Cliff Frensley, Sabrina N. Gates, Katie J. Glattfelder, Kevin R. Halverson, Matthew R. Hart, John G. Hohmann, Maureen P. Howell, Darren P. Jeung, Rebecca A. Johnson, Patrick T. Karr, Reena Kawal, Jolene M. Kidney, Rachel H. Knapik, Chihchau L. Kuan, James H. Lake, Annabel R. Laramee, Kirk D. Larsen, Christopher Lau, Tracy A. Lemon, Agnes J. Liang, Ying Liu, Lon T. Luong, Jesse Michaels, Judith J. Morgan, Rebecca J. Morgan, Marty T. Mortrud, Nerick F. Mosqueda, Lydia L. Ng, Randy Ng, Geralyn J. Orta, Caroline C. Overly, Tu H. Pak, Sheana E. Parry, Sayan D. Pathak, Owen C. Pearson, Ralph B. Puchalski, Zackery L. Riley, Hannah R. Rockett, Stephen A. Rowland, Joshua J. Royall, Marcos J. Ruiz, Nadia R. Sarno, Katherine Schaffnit, Nadiya V. Shapovalova, Taz Sivisay, Clifford R. Slaughterbeck, Simon C. Smith, Kimberly A. Smith, Bryan I. Smith, Andy J. Sodt, Nick N. Stewart, Kenda-Ruth Stumpf, Susan M. Sunkin, Madhavi Sutram, Angelene Tam, Carey D. Teemer, Christina Thaller, Carol L. Thompson, Lee R. Varnam, Axel Visel, Ray M. Whitlock, Paul E. Wohnoutka, Crissa K. Wolkey, Victoria Y. Wong, Matthew Wood, Murat B. Yaylaoglu, Rob C. Young, Brian L. Youngstrom, Xu Feng Yuan, Bin Zhang, Theresa A. Zwingman & Allan R. Jones
doi:10.1038/nature05453
Abstract | Full Text | PDF (2,960K) | Supplementary information
See also: Editor's summary | News and Views by Markram
Thymosin 
4 induces adult epicardial progenitor mobilization and neovascularization p177
Nicola Smart, Catherine A. Risebro, Athalie A. D. Melville, Kelvin Moses, Robert J. Schwartz, Kenneth R. Chien & Paul R. Riley
doi:10.1038/nature05383
Abstract | Full Text | PDF (2,575K) | Supplementary information
See also: Editor's summary
Letters
A black hole in a globular cluster p183
Thomas J. Maccarone, Arunav Kundu, Stephen E. Zepf & Katherine L. Rhode
doi:10.1038/nature05434
First paragraph | Full Text | PDF (157K)
See also: Editor's summary
Spin correlations in the electron-doped high-transition-temperature superconductor Nd2-xCexCuO4
p186
E. M. Motoyama, G. Yu, I. M. Vishik, O. P. Vajk, P. K. Mang & M. Greven
doi:10.1038/nature05437
First paragraph | Full Text | PDF (469K)
Quantification of actinide 
-radiation damage in minerals and ceramics p190
Ian Farnan, Herman Cho & William J. Weber
doi:10.1038/nature05425
First paragraph | Full Text | PDF (249K) | Supplementary information
See also: Editor's summary | News and Views by Ewing
Redox evolution of a degassing magma rising to the surface p194
Alain Burgisser & Bruno Scaillet
doi:10.1038/nature05509
First paragraph | Full Text | PDF (443K) | Supplementary information
See also: Editor's summary
Evidence of giant sulphur bacteria in Neoproterozoic phosphorites p198
Jake V. Bailey, Samantha B. Joye, Karen M. Kalanetra, Beverly E. Flood & Frank A. Corsetti
doi:10.1038/nature05457
First paragraph | Full Text | PDF (1,942K) | Supplementary information
See also: Editor's summary | News and Views by Donoghue
Habitat modification alters the structure of tropical host–parasitoid food webs p202
Jason M. Tylianakis, Teja Tscharntke & Owen T. Lewis
doi:10.1038/nature05429
First paragraph | Full Text | PDF (201K) | Supplementary information
See also: Editor's summary
A stomatin-domain protein essential for touch sensation in the mouse p206
Christiane Wetzel, Jing Hu, Dieter Riethmacher, Anne Benckendorff, Lena Harder, Andreas Eilers, Rabih Moshourab, Alexey Kozlenkov, Dominika Labuz, Ombretta Caspani, Bettina Erdmann, Halina Machelska, Paul A. Heppenstall & Gary R. Lewin
doi:10.1038/nature05394
First paragraph | Full Text | PDF (383K) | Supplementary information
See also: Editor's summary
Light stimulates growth of proteorhodopsin-containing marine Flavobacteria p210
Laura Gómez-Consarnau, José M. González, Montserrat Coll-Lladó, Pontus Gourdon, Torbjörn Pascher, Richard Neutze, Carlos Pedrós-Alió & Jarone Pinhassi
doi:10.1038/nature05381
First paragraph | Full Text | PDF (366K) | Supplementary information
See also: Editor's summary
Histone arginine methylation regulates pluripotency in the early mouse embryo p214
Maria-Elena Torres-Padilla, David-Emlyn Parfitt, Tony Kouzarides & Magdalena Zernicka-Goetz
doi:10.1038/nature05458
First paragraph | Full Text | PDF (1,657K) | Supplementary information
See also: Editor's summary | News and Views by Dell
The nuclear receptor LXR is a glucose sensor p219
Nico Mitro, Puiying A. Mak, Leo Vargas, Cristina Godio, Eric Hampton, Valentina Molteni, Andreas Kreusch & Enrique Saez
doi:10.1038/nature05449
First paragraph | Full Text | PDF (404K) | Supplementary information
Naturejobs
ProspectThe growing involvement of contract research organizations in drug development could result in job shifts. p225
Paul Smaglik
doi:10.1038/nj7124-225a
Recruitment
Following the law p228
A guide for the perplexed graduate student doing research.
Irving P. Herman
doi:10.1038/nj7124-228a
Highlights
Special Feature: NIH
doi:10.1038/nj0141
Career View
Summit cum laude
Milan de Vries is a molecular-biology graduate student at the Massachusetts Institute of Technology.
Milan de Vries
doi:10.1038/nj0142