Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 445, 31-33 (4 January 2007) | doi:10.1038/445031a; Published online 3 January 2007
Open Innovation Challenges
-
Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
-
Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
- More Challenges
- Powered by:
nature jobs
Canada Excellence Research Chair in Biofuels and Biorefining Innovation
- University of British Columbia
- Vancouver, British Columbia Canada
Scientist, Plant Biochemist
- Philip Morris International (PMI)
- Neuchatel, Switzerland
Bioorganic chemistry: A sweet synthesis
Linda C. Hsieh-Wilson1
Abstract
Peptides and proteins with sugars attached have many desirable biological properties, but their chemical synthesis is a technical challenge. An ingenious take on an old idea might simplify things considerably.
Part of what distinguishes us from bacteria is that the proteins in our bodies are decorated with elaborate arrays of sugars. Protein glycosylation — the attachment of sugars to the amino-acid building-blocks of proteins — plays a crucial role in such diverse processes as protein folding, cell–cell communication and viral invasion of cells.
- Linda C. Hsieh-Wilson is at the California Institute of Technology and Howard Hughes Medical Institute, Division of Chemistry and Chemical Engineering, 1200 East California Boulevard, Pasadena, California 91125, USA.
Email: lhw@caltech.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Mass spectrometry provides sweet inspirationNature Biotechnology News and Views (01 Jun 2003)
RESEARCH
X-ray structure of 5-aminolaevulinate dehydratase, a hybrid aldolaseNature Structural Biology Article (01 Dec 1997)
Emerging themes in medicinal glycoscienceNature Biotechnology Research (01 Aug 2000)
