Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 445, 31-33 (4 January 2007) | doi:10.1038/445031a; Published online 3 January 2007
Open Innovation Challenges
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
-
Methods of Modeling Adaptation in Populations
The analysis of adaptation with a population is a frequently encountered computational modeling scen...
- More Challenges
- Powered by:
nature jobs
Director
- The National Center for Complementary and Alternative Medicine (NCCAM)
- Bethesda, MD
Faculty Positions
- University of Texas Medical Branch
- Galveston, TX United States
Bioorganic chemistry: A sweet synthesis
Linda C. Hsieh-Wilson1
Abstract
Peptides and proteins with sugars attached have many desirable biological properties, but their chemical synthesis is a technical challenge. An ingenious take on an old idea might simplify things considerably.
Part of what distinguishes us from bacteria is that the proteins in our bodies are decorated with elaborate arrays of sugars. Protein glycosylation — the attachment of sugars to the amino-acid building-blocks of proteins — plays a crucial role in such diverse processes as protein folding, cell–cell communication and viral invasion of cells.
- Linda C. Hsieh-Wilson is at the California Institute of Technology and Howard Hughes Medical Institute, Division of Chemistry and Chemical Engineering, 1200 East California Boulevard, Pasadena, California 91125, USA.
Email: lhw@caltech.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Mass spectrometry provides sweet inspirationNature Biotechnology News and Views (01 Jun 2003)
