Provider: Nature Publishing Group
Content: application/x-research-info-systems
TY  - JOUR
AU  - Simpson, L. L.
TI  - Identification of the characteristics that underlie botulinum toxin potency: implications for designing novel drugs
JA  - Biochimie
PY  - 2000///
VL  - 82
SP  - 943
EP  - 953
M3  - 10.1016/S0300-9084(00)01169-X
N1  - 10.1016/S0300-9084(00)01169-X
UR  - http://dx.doi.org/10.1016/S0300-9084(00)01169-X
ER  -

TY  - JOUR
AU  - Montecucco, C.
TI  - How do tetanus and botulinum toxins bind to neuronal membranes?
JA  - Trends Biochem. Sci.
PY  - 1986///
VL  - 11
SP  - 315
EP  - 317
M3  - 10.1016/0968-0004(86)90282-3
N1  - 10.1016/0968-0004(86)90282-3
UR  - http://dx.doi.org/10.1016/0968-0004(86)90282-3
ER  -

TY  - JOUR
AU  - Mahrhold, S.
AU  - Rummel, A.
AU  - Bigalke, H.
AU  - Davletov, B.
AU  - Binz, T.
TI  - The synaptic vesicle protein 2C mediates the uptake of botulinum neurotoxin A into phrenic nerves
JA  - FEBS Lett.
PY  - 2006///
VL  - 580
SP  - 2011
EP  - 2014
M3  - 10.1016/j.febslet.2006.02.074
N1  - 10.1016/j.febslet.2006.02.074
UR  - http://dx.doi.org/10.1016/j.febslet.2006.02.074
ER  -

TY  - JOUR
AU  - Dong, M.
TI  - SV2 is the protein receptor for botulinum neurotoxin A
JA  - Science
PY  - 2006///
VL  - 312
SP  - 592
EP  - 596
M3  - 10.1126/science.1123654
N1  - 10.1126/science.1123654
UR  - http://dx.doi.org/10.1126/science.1123654
ER  -

TY  - JOUR
AU  - Nishiki, T.
TI  - The high-affinity binding of Clostridium botulinum type B neurotoxin to synaptotagmin II associated with gangliosides GT1b/GD1a
JA  - FEBS Lett.
PY  - 1996///
VL  - 378
SP  - 253
EP  - 257
M3  - 10.1016/0014-5793(95)01471-3
N1  - 10.1016/0014-5793(95)01471-3
UR  - http://dx.doi.org/10.1016/0014-5793(95)01471-3
ER  -

TY  - JOUR
AU  - Dong, M.
TI  - Synaptotagmins I and II mediate entry of botulinum neurotoxin B into cells
JA  - J. Cell Biol.
PY  - 2003///
VL  - 162
SP  - 1293
EP  - 1303
M3  - 10.1083/jcb.200305098
N1  - 10.1083/jcb.200305098
UR  - http://dx.doi.org/10.1083/jcb.200305098
ER  -

TY  - JOUR
AU  - Rummel, A.
AU  - Karnath, T.
AU  - Henke, T.
AU  - Bigalke, H.
AU  - Binz, T.
TI  - Synaptotagmins I and II act as nerve cell receptors for botulinum neurotoxin G
JA  - J. Biol. Chem.
PY  - 2004///
VL  - 279
SP  - 30865
EP  - 30870
M3  - 10.1074/jbc.M403945200
N1  - 10.1074/jbc.M403945200
UR  - http://dx.doi.org/10.1074/jbc.M403945200
ER  -

TY  - JOUR
AU  - Nishiki, T.
TI  - Binding of botulinum type B neurotoxin to Chinese hamster ovary cells transfected with rat synaptotagmin II cDNA
JA  - Neurosci. Lett.
PY  - 1996///
VL  - 208
SP  - 105
EP  - 108
M3  - 10.1016/0304-3940(96)12557-X
N1  - 10.1016/0304-3940(96)12557-X
UR  - http://dx.doi.org/10.1016/0304-3940(96)12557-X
ER  -

TY  - JOUR
AU  - Swaminathan, S.
AU  - Eswaramoorthy, S.
TI  - Structural analysis of the catalytic and binding sites of Clostridium botulinum neurotoxin B
JA  - Nature Struct. Biol.
PY  - 2000///
VL  - 7
SP  - 693
EP  - 699
M3  - 10.1038/78005
N1  - 10.1038/78005
UR  - http://dx.doi.org/10.1038/78005
ER  -

TY  - JOUR
AU  - Breidenbach, M. A.
AU  - Brunger, A. T.
TI  - Substrate recognition strategy for botulinum neurotoxin serotype A
JA  - Nature
PY  - 2004///
VL  - 432
SP  - 925
EP  - 929
M3  - 10.1038/nature03123
N1  - 10.1038/nature03123
UR  - http://dx.doi.org/10.1038/nature03123
ER  -

TY  - JOUR
AU  - Simpson, L. L.
TI  - Identification of the major steps in botulinum toxin action
JA  - Annu. Rev. Pharmacol. Toxicol.
PY  - 2004///
VL  - 44
SP  - 167
EP  - 193
M3  - 10.1146/annurev.pharmtox.44.101802.121554
N1  - 10.1146/annurev.pharmtox.44.101802.121554
UR  - http://dx.doi.org/10.1146/annurev.pharmtox.44.101802.121554
ER  -

TY  - JOUR
AU  - Jayaraman, S.
AU  - Eswaramoorthy, S.
AU  - Kumaran, D.
AU  - Swaminathan, S.
TI  - Common binding site for disialyllactose and tri-peptide in C-fragment of tetanus neurotoxin
JA  - Proteins
PY  - 2005///
VL  - 61
SP  - 288
EP  - 295
M3  - 10.1002/prot.20595
N1  - 10.1002/prot.20595
UR  - http://dx.doi.org/10.1002/prot.20595
ER  -

TY  - JOUR
AU  - Lacy, D. B.
AU  - Tepp, W.
AU  - Cohen, A. C.
AU  - DasGupta, B. R.
AU  - Stevens, R. C.
TI  - Crystal structure of botulinum neurotoxin type A and implications for toxicity
JA  - Nature Struct. Biol.
PY  - 1998///
VL  - 5
SP  - 898
EP  - 902
M3  - 10.1038/2338
N1  - 10.1038/2338
UR  - http://dx.doi.org/10.1038/2338
ER  -

TY  - JOUR
AU  - Schiavo, G.
AU  - Matteoli, M.
AU  - Montecucco, C.
TI  - Neurotoxins affecting neuroexocytosis
JA  - Physiol. Rev.
PY  - 2000///
VL  - 80
SP  - 717
EP  - 766
ER  -

TY  - JOUR
AU  - Kitamura, M.
AU  - Takamiya, K.
AU  - Aizawa, S.
AU  - Furukawa, K.
TI  - Gangliosides are the binding substances in neural cells for tetanus and botulinum toxins in mice
JA  - Biochim. Biophys. Acta
PY  - 1999///
VL  - 1441
SP  - 1
EP  - 3
ER  -

TY  - JOUR
AU  - Kozaki, S.
AU  - Kamata, Y.
AU  - Watarai, S.
AU  - Nishiki, T.
AU  - Mochida, S.
TI  - Ganglioside GT1b as a complementary receptor component for Clostridium botulinum neurotoxins
JA  - Microbiol. Pathol.
PY  - 1998///
VL  - 25
SP  - 91
EP  - 99
ER  -

TY  - JOUR
AU  - Rummel, A.
AU  - Mahrhold, S.
AU  - Bigalke, H.
AU  - Binz, T.
TI  - The H-CC-domain of botulinum neurotoxins A and B exhibits a singular ganglioside binding site displaying serotype specific carbohydrate interaction
JA  - Mol. Microbiol.
PY  - 2004///
VL  - 51
SP  - 631
EP  - 643
M3  - 10.1046/j.1365-2958.2003.03872.x
N1  - 10.1046/j.1365-2958.2003.03872.x
UR  - http://dx.doi.org/10.1046/j.1365-2958.2003.03872.x
ER  -

TY  - JOUR
AU  - Ginalski, K.
AU  - Venclovas, C.
AU  - Lesyng, B.
AU  - Fidelis, K.
TI  - Structure-based sequence alignment for the beta-trefoil subdomain of the clostridial neurotoxin family provides residue level information about the putative ganglioside binding site
JA  - FEBS Lett.
PY  - 2000///
VL  - 482
SP  - 119
EP  - 124
M3  - 10.1016/S0014-5793(00)01954-2
N1  - 10.1016/S0014-5793(00)01954-2
UR  - http://dx.doi.org/10.1016/S0014-5793(00)01954-2
ER  -

TY  - JOUR
AU  - Yowler, B. C.
AU  - Kensinger, R. D.
AU  - Schengrund, C. L.
TI  - Botulinum neurotoxin A activity is dependent upon the presence of specific gangliosides in neuroblastoma cells expressing synaptotagmin I
JA  - J. Biol. Chem.
PY  - 2002///
VL  - 277
SP  - 32815
EP  - 32819
M3  - 10.1074/jbc.M205258200
N1  - 10.1074/jbc.M205258200
UR  - http://dx.doi.org/10.1074/jbc.M205258200
ER  -

TY  - JOUR
AU  - Rummel, A.
AU  - Bade, S.
AU  - Alves, J.
AU  - Bigalke, H.
AU  - Binz, T.
TI  - Two carbohydrate binding sites in the H-cc-domain of tetanus neurotoxin are required for toxicity
JA  - J. Mol. Biol.
PY  - 2003///
VL  - 326
SP  - 835
EP  - 847
M3  - 10.1016/S0022-2836(02)01403-1
N1  - 10.1016/S0022-2836(02)01403-1
UR  - http://dx.doi.org/10.1016/S0022-2836(02)01403-1
ER  -

TY  - JOUR
AU  - Fotinou, C.
TI  - The crystal structure of tetanus toxin Hc fragment complexed with a synthetic GT1b analogue suggests cross-linking between ganglioside receptors and the toxin
JA  - J. Biol. Chem.
PY  - 2001///
VL  - 276
SP  - 32274
EP  - 32281
M3  - 10.1074/jbc.M103285200
N1  - 10.1074/jbc.M103285200
UR  - http://dx.doi.org/10.1074/jbc.M103285200
ER  -

TY  - JOUR
AU  - Weis, W. I.
TI  - Cell-surface carbohydrate recognition by animal and viral lectins
JA  - Curr. Opin. Struct. Biol.
PY  - 1997///
VL  - 7
SP  - 624
EP  - 630
M3  - 10.1016/S0959-440X(97)80070-X
N1  - 10.1016/S0959-440X(97)80070-X
UR  - http://dx.doi.org/10.1016/S0959-440X(97)80070-X
ER  -

TY  - JOUR
AU  - Eswaramoorthy, S.
AU  - Kumaran, D.
AU  - Keller, J.
AU  - Swaminathan, S.
TI  - Role of metals in the biological activity of Clostridium botulinum neurotoxins
JA  - Biochemistry
PY  - 2004///
VL  - 43
SP  - 2209
EP  - 2216
M3  - 10.1021/bi035844k
N1  - 10.1021/bi035844k
UR  - http://dx.doi.org/10.1021/bi035844k
ER  -

TY  - JOUR
AU  - Otwinowski, Z.
AU  - Minor, W.
TI  - Processing of X-ray diffraction data collected in oscillation mode
JA  - Meth. Enzymol.
PY  - 1997///
VL  - 276
SP  - 307
EP  - 326
M3  - 10.1016/S0076-6879(97)76066-X
N1  - 10.1016/S0076-6879(97)76066-X
UR  - http://dx.doi.org/10.1016/S0076-6879(97)76066-X
ER  -

TY  - JOUR
AU  - Vagin, A.
AU  - Teplyakov, A.
TI  - MOLREP: an automated program for molecular replacement
JA  - J. Appl. Cryst.
PY  - 1997///
VL  - 30
SP  - 1022
EP  - 1025
M3  - 10.1107/S0021889897006766
N1  - 10.1107/S0021889897006766
UR  - http://dx.doi.org/10.1107/S0021889897006766
ER  -

TY  - JOUR
AU  - Emsley, P.
AU  - Cowtan, K.
TI  - Coot: model-building tools for molecular graphics
JA  - Acta Crystallogr.
PY  - 2004///
VL  - D 60
SP  - 2126
EP  - 2132
ER  -

TY  - JOUR
TI  - The CCP4 suite: programs for protein crystallography
JA  - Acta Crystallogr.
PY  - 1994///
VL  - D 50
SP  - 760
EP  - 763
ER  -

TY  - JOUR
AU  - Cheng, Y.
TI  - Crystallographic identification of Ca2+ and Sr2+ coordination sites in synaptotagmin I C2B domain
JA  - Protein Sci.
PY  - 2004///
VL  - 13
SP  - 2665
EP  - 2672
M3  - 10.1110/ps.04832604
N1  - 10.1110/ps.04832604
UR  - http://dx.doi.org/10.1110/ps.04832604
ER  -

TY  - JOUR
AU  - Sutton, R. B.
AU  - Ernst, J. A.
AU  - Brunger, A. T.
TI  - Crystal structure of the cytosolic C2A-C2B domains of synaptotagmin III. Implications for Ca2+-independent SNARE complex interaction
JA  - J. Cell Biol.
PY  - 1999///
VL  - 147
SP  - 589
EP  - 598
M3  - 10.1083/JCB.147.3.589
N1  - 10.1083/JCB.147.3.589
UR  - http://dx.doi.org/10.1083/JCB.147.3.589
ER  -