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Nature 444, 1096-1100 (13 December 2006) | doi:10.1038/nature05411;
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Structural basis of cell surface receptor recognition by botulinum neurotoxin B
Botulinum neurotoxins (BoNTs) are potent bacterial toxins that cause paralysis at femtomolar concentrations by blocking neurotransmitter release. A |[lsquo]|double receptor|[rsquo]| model has been proposed in which BoNTs recognize nerve terminals via interactions with both gangliosides and protein receptors that mediate their entry.
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